Pregled bibliografske jedinice broj: 457055
Bioconjugates of 1’-Aminoferrocene-1-carboxylic Acid with (S)-3-Amino-2-methylpropanoic Acid and L-Alanine
Bioconjugates of 1’-Aminoferrocene-1-carboxylic Acid with (S)-3-Amino-2-methylpropanoic Acid and L-Alanine // European journal of inorganic chemistry, 2010 (2010), 7; 1089-1097 doi:10.1002/ejic.200901146 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 457055 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Bioconjugates of 1’-Aminoferrocene-1-carboxylic Acid with (S)-3-Amino-2-methylpropanoic Acid and L-Alanine
Autori
Čakić Semenčić, Mojca ; Heinze, Katja ; Forster, Christoph ; Rapić, Vladimir
Izvornik
European journal of inorganic chemistry (1434-1948) 2010
(2010), 7;
1089-1097
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
bioorganometallic chemistry ; beta-amino acid ; ferrocene ; hydrogen bonds ; conformational analysis
Sažetak
Formal CH2 insertion in bioconjugates composed of 1’-aminoferrocene-1-carboxylic acid (Fca) and alanine Boc-Ala-Fca-Ala-OCH3 gives Fca conjugates with the beta-amino acid (S)-3-amino-2-methylpropanoic acid (Aib). “L-Ala–to–(S)-beta-Aib mutations” exert ferrocene helix inversion and (de-)stabilize the secondary structure depending on the “mutation site” as shown by NMR, CD and IR spectroscopy in concert with DFT calculations.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
058-1191344-3122 - Metalocenski biokonjugati, heterocikli i makromolekule (Kovač, Veronika, MZOS ) ( CroRIS)
Ustanove:
Prehrambeno-biotehnološki fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
