Naslov
Hrvatske smjernice za prevenciju mučnine i povraćanja
(Cratian guideliness for prevention of chemotherapy induced nausea and vomitin)

Autori
Tomek, Rudolf ; Vrdoljak, Eduard ; Vrbanec, Damir ; Nemet, Damir ; Matković, Višnja ; Pleština, Stjepko ; Gugić, Damir ; Dobrila- Dintinjana, Renata ; Bolanča, Ante ; Samardžija, Miro ; Petković, Marija

Izvornik
Liječnički vjesnik : glasilo Hrvatskoga liječničkog zbora (0024-3477) 131 (2009), (3-4); 49-53

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, uvodnik, ostalo

Ključne riječi
protutumorski lijekovi ; neželjeni učinci ; mučnina ; prevencija
(antineoplastic agents ; adverse effects ; nausea ; vomiting ; prevention)

Sažetak
Approximately 70-80% of all cancer patients receiving chemotherapy experience nausea and/or vomiting. Nausea and vomiting are important side effects of cancer treatment, which can significantly affect a patient's quality of life, leading to poor compliance with further chemotherapy treatment. The main principle of emesis control is prevention. Currently available antiemetic agents corticosteroids, 5- hydroxytriptamine receptor antagonists, and neurokinin-1 antagonists, are used alone or in combination. Antiemetic regimen should be chosen based on the emetogenic potential of the chemotherapy regimen, previous experience with antiemetics, and patient-specific risk factors. Newer agents, including second generation 5-HT3 receptor antagonist palonosetron and the NK-1 antagonist aprepitant, offer additional clinical benefit in highly and moderately emetogenic therapy, especially in delayed nausea and vomiting. The aim of this Guidelines is to achieve same standards of care in the treatment of nausea and vomiting across Croatia that are applicable in our environment--only available drugs are included in the Guidelines.

Izvorni jezik
Hrvatski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA