Pregled bibliografske jedinice broj: 437699
Immune response to surgical stress in spinal anaesthesia
Immune response to surgical stress in spinal anaesthesia // Periodicum biologorum, 111 (2009), 2; 193-196 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 437699 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Immune response to surgical stress in spinal anaesthesia
Autori
Žura, Marijana ; Šakić, Katarina ; Malenica, Branko ; Vrbanović, Vilena
Izvornik
Periodicum biologorum (0031-5362) 111
(2009), 2;
193-196
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
spinal anaesthesia; cytokines; immunology
Sažetak
Regional techniques, such as epidural or spinal anaesthesia , with an afferent neural block by local anaesthetics profoundly inhibit hormonal and metabolic stress response. Surgery-related postoperative release of the proinflammatory cytokine IL-6 was increased in patients after spinal anaesthesia with no increased levels of the typical Th1 cytokine IFN-gama and no increase of cytokines such as IL-10 and IL-4, which are associated with T helper type 2 ( Th2)-like immune response. Spinal anaesthesi results in less immunosuppression , i.e. maintains the number of Th1 cells, thus stimulating the cell immunity.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
108-0000000-3433 - Imunosni odgovor na kirurški stres u regionalnoj i općoj anesteziji (Šakić, Kata, MZOS ) ( CroRIS)
214-1081874-0168 - Regulacijski limfociti u sistemskim autoimunim bolestima (Malenica, Branko, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
