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Pregled bibliografske jedinice broj: 4257

Liver regeneration in MHC class I deficient mice : Relationship to NK1.1. cells

Radošević-Stašić, Biserka; Trobonjača, Zlatko; Ćuk, Mira; Ravlić-Gulan, Jagoda; Mrakovčić-Šutić, Ines; Rukavina, Daniel
Liver regeneration in MHC class I deficient mice : Relationship to NK1.1. cells // 4th International Congress on the Immune Consequences of Trauma, Shock and Sepsis : Mechanisms and Therapeutic Approaches : Abstracts. / Faist E (ur.).
Bolonja: Monduzzi Editore, 1997. str. 521-526 (predavanje, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)

CROSBI ID: 4257 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Liver regeneration in MHC class I deficient mice : Relationship to NK1.1. cells

Autori
Radošević-Stašić, Biserka ; Trobonjača, Zlatko ; Ćuk, Mira ; Ravlić-Gulan, Jagoda ; Mrakovčić-Šutić, Ines ; Rukavina, Daniel

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
4th International Congress on the Immune Consequences of Trauma, Shock and Sepsis : Mechanisms and Therapeutic Approaches : Abstracts. / Faist E - Bolonja : Monduzzi Editore, 1997, 521-526

Skup
4th International Congress on the Immune Consequences of Trauma, Shock and Sepsis : Mechanisms and Therapeutic Approaches

Mjesto i datum
München, Njemačka, 04.03.1997. - 08.03.1997

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
liver regeneration; beta2- microglobulin deficient mice; MHC class I antigens; in vivo depletion of NK1.1. cells; extrathymic lymphopoesis; negative selection in the thymus

Sažetak
Owing to the role of MHC class I molecules and liver resident NK cells in the control of liver regeneration after partial hepatectomy (pHx) the effects of in vivo treatment with anti NK.1.1. mAb is analyzed in beta2 microglobulin (b2-m) deficient mice. The data showed that S phase of hepatocytes from NK1.1. -depleted b2-m +/- mice was increased (1st and 2nd day after pHx), in contrast to b2-m-/- mice, where, an inhibitory effect was seen (1st p.o.day). Simultaneously, in b2-m+/- mice a significant decline of CD5+, CD8+, TCRalpha, beta+ cells, Vbeta8+ and CD8+CD5+ intrahepatic cells was found, while in b2-m-/- mice an initial increase of CD5+, CD3+, Vbeta6+ , Vbeta8+ cells was seen. Enhancing effect on hepatocytes was only in MHC Class I expressing mice followed by antiNK1.1. insensitive decline of CD4+CD8+ T cells in thymus. The data point to different types of lymphoid cells participating in the control of liver growth and to the activation of procceses of negative selection after pHx.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA

Projekti:
062002

Ustanove:
Medicinski fakultet, Rijeka

Profili:

Avatar Url Mira Ćuk (autor)

Avatar Url Jagoda Ravlić-Gulan (autor)

Avatar Url Ines Mrakovčić-Šutić (autor)

Avatar Url Biserka Radošević-Stašić (autor)

Avatar Url Zlatko Trobonjača (autor)

Avatar Url Daniel Rukavina (autor)

Citiraj ovu publikaciju:

Radošević-Stašić, Biserka; Trobonjača, Zlatko; Ćuk, Mira; Ravlić-Gulan, Jagoda; Mrakovčić-Šutić, Ines; Rukavina, Daniel
Liver regeneration in MHC class I deficient mice : Relationship to NK1.1. cells // 4th International Congress on the Immune Consequences of Trauma, Shock and Sepsis : Mechanisms and Therapeutic Approaches : Abstracts. / Faist E (ur.).
Bolonja: Monduzzi Editore, 1997. str. 521-526 (predavanje, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)
Radošević-Stašić, B., Trobonjača, Z., Ćuk, M., Ravlić-Gulan, J., Mrakovčić-Šutić, I. & Rukavina, D. (1997) Liver regeneration in MHC class I deficient mice : Relationship to NK1.1. cells. U: Faist E (ur.)4th International Congress on the Immune Consequences of Trauma, Shock and Sepsis : Mechanisms and Therapeutic Approaches : Abstracts..
@article{article, author = {Rado\v{s}evi\'{c}-Sta\v{s}i\'{c}, Biserka and Trobonja\v{c}a, Zlatko and \'{C}uk, Mira and Ravli\'{c}-Gulan, Jagoda and Mrakov\v{c}i\'{c}-\v{S}uti\'{c}, Ines and Rukavina, Daniel}, year = {1997}, pages = {521-526}, keywords = {liver regeneration, beta2- microglobulin deficient mice, MHC class I antigens, in vivo depletion of NK1.1. cells, extrathymic lymphopoesis, negative selection in the thymus}, title = {Liver regeneration in MHC class I deficient mice : Relationship to NK1.1. cells}, keyword = {liver regeneration, beta2- microglobulin deficient mice, MHC class I antigens, in vivo depletion of NK1.1. cells, extrathymic lymphopoesis, negative selection in the thymus}, publisher = {Monduzzi Editore}, publisherplace = {M\"{u}nchen, Njema\v{c}ka} }
@article{article, author = {Rado\v{s}evi\'{c}-Sta\v{s}i\'{c}, Biserka and Trobonja\v{c}a, Zlatko and \'{C}uk, Mira and Ravli\'{c}-Gulan, Jagoda and Mrakov\v{c}i\'{c}-\v{S}uti\'{c}, Ines and Rukavina, Daniel}, year = {1997}, pages = {521-526}, keywords = {liver regeneration, beta2- microglobulin deficient mice, MHC class I antigens, in vivo depletion of NK1.1. cells, extrathymic lymphopoesis, negative selection in the thymus}, title = {Liver regeneration in MHC class I deficient mice : Relationship to NK1.1. cells}, keyword = {liver regeneration, beta2- microglobulin deficient mice, MHC class I antigens, in vivo depletion of NK1.1. cells, extrathymic lymphopoesis, negative selection in the thymus}, publisher = {Monduzzi Editore}, publisherplace = {M\"{u}nchen, Njema\v{c}ka} }

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