Naslov
Growth and Biosynthesis of Aflatoxin in Presence of Newly Synthesized Analogues of Dehydroacetic Acid

Autori
Duraković, Lejla ; Delaš, Frane ; Markov, Ksenija ; Duraković, Senadin

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Proceedings of the 2nd Central European Meeting 5th Croatian Congress of Food Technologists, Biotechnologists and Nutritionists / Karlović, D. - Zagreb : Hrvatsko društvo za prehrambenu tenologiju, biotehnologiju i nutricionizam, 2004, 366-370

ISBN
953-99725-1-5

Skup
2nd Central European Meeting 5th Croatian Congress of Food Technologists, Biotechnologists and Nutritionists

Mjesto i datum
Opatija, Hrvatska, 17.10.2004. - 20.10.2004

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Mycotoxins in Food; Aspergillus flavus; Aflatoxins B1 and G1; Biosynthesis; DHA; DHT; BrDHT

Sažetak
Mycelial growth and toxin accumulation by Aspergillus flavus were inhibited by dehydroacetic acid (DHA) and its newly synthesized analogues, 4-hydroxy-3-(p-toluoyl)-6-(p-tolil)-2H-pyrane-2-one (DHT) and 5-bromo-4-hydroxy-3-(p-toluoyl)-6-(p-tolil)-2H-pyrane-2-one (BrDHT) concentrations higher than 12.0 M x L-1.When fungus was grown in broth, mould growth was reduced by 25% at a DHT concentration of 160 μ M x L-1, and aflatoxin B1 (AFB1) and aflatoxin G1 (AFG1) concentrations were reduced by 5% and 14%, respectively.In experiments with 2.5 and 25.0 μ M x L-1 of BrDHT, the maximum mould growth was 70% and 55% of that in the control broth.A 2.5 μ M x L-1 BrDHT concentration reduced the production of both investigated toxins to 92% and 85%, respectively.At 25.0 μ M of BrDHT, accumulation of AFB1 was 80% of that in control experiments, whereas the accumulation of AFG1 was 75% of the control value.In the media containing 125.0 μ M of BrDHT, the accumulation of aflatoxins was reduced to 45% and 60% of the control values.The growth of mould biomass was reduced by 35%.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

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