Naslov
A one-pot synthesis and structure determination of 3-(1-phenyl-5-p-tolylpyrazol-3-yl)2-p-tolylindole ethanol solvate

Autori
Jukić, Marijana ; Cetina, Mario ; Pavlović, Gordana ; Rapić, Vladimir

Izvornik
Structural chemistry (1040-0400) 10 (1999), 2; 85-90

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
1; 5-di(p-tolyl)pentane-1; 3; 5-trione; phenylhydrazine hydrochloride; Fischer indole cyclization; X-ray analysis; spectroscopic characterization

Sažetak
The Fischer indolization afforded the title compound, C_31H_25N_3xC_2H_5OH, as the major product in the reaction of 1, 5-di(p-tolyl)-pentane-1, 3, 5-trione with phenylhydrazine hydrochloride in ethanol. The structure assignment of this novel pyrazolylindole derivative is based on the data of elemental analysis, IR, 1^H NMR and 13^C NMR spectroscopy. The structure is also confirmed by means of X-ray crystallography. The molecule crystallizes in the orthorhombic space group P 2_12_12_1, with a = 10.298(2), b = 14.984(5), c = 18.133(3) A, Z = 8, V = 2798.0(12) A^3. The absolute structure has been determined. The ethanol molecule forms intermolecular hydrogen bonds with the pyrazole and indole nitrogen atoms.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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