Naslov
Influence of 2-deoxy-D-glucose on cell growth of the yeast Saccharomyces cerevisiae

Autori
Matošić, Marin ; Novak, Srđan ; Marić, Vladimir

Izvornik
Food technology and biotechnology (1330-9862) 34 (1996), 2-3; 97-100

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
S. cerevisiae ; cell growth ; 2-deoxy-D-glucose ; inhibitory effects ; glucose repression

Sažetak
2-deoxy-D-glucose (2-DOG) causes two main effects in the yeast Saccharomyces cerevisiae: the first is glucose repression and the second is an inhibitory effect caused by a disturbance of cell metabolism. In this work we have studied both effects of 2-DOG on yeast metabolism and their influence on substrate uptake and growth of biomass. The effect of glucose repression on galactose grown cells was observed at 2-DOG concentration of 20 mg/l, and growth was stopped completely at concentration of 50 mg/l. The inhibitory mode of action occurred at a concentrations higher than 300 mg/l.

Izvorni jezik
Engleski

Znanstvena područja
Prehrambena tehnologija

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