Pregled bibliografske jedinice broj: 414203
Pyostomatitis vegetans associated with inflammatory bowel disease : report of two cases
Pyostomatitis vegetans associated with inflammatory bowel disease : report of two cases // 5. kongres Hrvatskog gastroenterološkog društva s međunarodnim sudjelovanjem : knjiga sažetaka
Dubrovnik, Hrvatska, 2009. str. 72-72 (poster, domaća recenzija, sažetak, stručni)
CROSBI ID: 414203 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Pyostomatitis vegetans associated with inflammatory bowel disease : report of two cases
Autori
Mijandrušić-Sinčić, Brankica ; Licul, Vanja ; Muhvić-Urek, Miranda ; Glažar, Irena ; Juretić, Mirna ; Lučin, Ksenija ; Štimac, Davor
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni
Izvornik
5. kongres Hrvatskog gastroenterološkog društva s međunarodnim sudjelovanjem : knjiga sažetaka
/ - , 2009, 72-72
Skup
Kongres Hrvatskog gastroenterološkog društva s međunarodnim sudjelovanjem (5 ; 2009)
Mjesto i datum
Dubrovnik, Hrvatska, 03.04.2009. - 05.04.2009
Vrsta sudjelovanja
Poster
Vrsta recenzije
Domaća recenzija
Ključne riječi
ulcerative colitis; Crohn disease; pyostomatitis vegetans
Sažetak
Pyostomatitis vegentans (PV) is rare benign mucocutaneus disorder usually associated with inflammatory bowel disease (IBD). We present two cases of PV associate with Crohn's disease (CD) and ulcerative colitis (UC) as well. Clinical cases: A 23-year-old woman with a history of luminal, cortisteroid dependent CD of terminal ileum and colon experienced acute pancreatitis caused by azatioprin. During pretreatment screening for biologic therapy she presented with yellow, linear pustules and multiple, little painful ulceration on erythematous labial and buccal mucosa. Deep fissures were presented on ventral tongue. The histological report revealed PV. We started with adalimumab therapy and she achieved remission of intestinal and oral pathology. A 32-year-old woman with UC presented with yellowish, slightly elevated, pustules set on an erythematous soft palatal mucosa and dorsal tongue mucosa, after stopping corticosteroid therapy. Patient was complained to severe pain which interfered with food ingestion. Histological examination showed intraepithelial and subepithelal exudate containing numerous granulocytes including eosinophils. In subepithelial stromal tissue, a mixed inflamatory infiltrate containing granulocytes, lymphocytes and plasma cells was found. We restarted with steroids and oral pathology disappeared. After discontinuing of steroids she had a recurrent of the oral manifestation, and azatioprin was added. Complete remission of PV was achieved. Later, because of persistent active colonic disease in spite of immunomodulatory therapy we started with infliximab. Our cases confirm previously reported good experience with immunomodulators and biologics in the treatment of PV. But, before using them we have to exclude an infectious etiology of PV.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
062-0000000-0219 - Genetsko testiranje bolesnika s kroničnim bolestima tankoga crijeva (Mijandrušić-Sinčić, Brankica, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Rijeka
Profili:
Mirna Juretić
(autor)
Vanja Licul
(autor)
Marija Crnčević Urek
(autor)
Davor Štimac
(autor)
Brankica Mijandrušić-Sinčić
(autor)
Irena Glažar
(autor)
Miranda Muhvić-Urek
(autor)
Ksenija Jurinović
(autor)