Pregled bibliografske jedinice broj: 409556
Results of cytogenetical analysis of 1194 chordocenteses
Results of cytogenetical analysis of 1194 chordocenteses // ESHG
Nica, Francuska, 2007. (poster, međunarodna recenzija, sažetak, ostalo)
CROSBI ID: 409556 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Results of cytogenetical analysis of 1194 chordocenteses
Autori
Burek, M ; Letica, L ; Lasan, R ; Ljubic, H ; Muzinic, D ; Begovic, D
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo
Izvornik
ESHG
/ - , 2007
Skup
European HUMAN GENETICS Conference 2007
Mjesto i datum
Nica, Francuska, 16.06.2007. - 19.06.2007
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Cytogenetical analysis; Chordocenteses
Sažetak
1194 chordocenteses were analyzed cytogenetically in a period of 22 years, using cytogenetical GTG-banding method. Indications for chordocenteses were late weeks of pregnancy (ultrasound markers, parents carrieres of reciprocal translocation, age, … ) and amniocenteses From total number of 1194 chordocenteses, 88 (7, 37 %) were karyotypically determined as pathologic: 63 (71, 5 %) numerical aberrations and 25 (28, 4 %) structural aberrations. The most frequent numerical aberrations were trisomie of chromosome 21 (21/63 ; 33.3 %) and trisomie of chromosome 18 (20/63 ; 31.7 %). Pathology in amniocenteses were confirmed with almost 100 % accuracy with chordocenteses. Considering other indications for chordocentesis, most pathologic karyotypes were confirmed at ultrasound markers indication (45/60 ; 75%).
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
108-0000000-0353 - Novi pristupi dijagnostici nasljednih bolesti (Begović, Davor, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Zagreb
Profili:
Ružica Lasan Trčić
(autor)
Dubravka Mužinić-Belinec
(autor)
Davor Begović
(autor)
Ljiljana Letica
(autor)