Pregled bibliografske jedinice broj: 409276
Gender and Trisomy 21 Analysis on Aborted Fetus Tissue
Gender and Trisomy 21 Analysis on Aborted Fetus Tissue // Acta Clinica Croatica
Zagreb, Hrvatska, 2008. str. 52-53 (predavanje, nije recenziran, sažetak, stručni)
CROSBI ID: 409276 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Gender and Trisomy 21 Analysis on Aborted Fetus Tissue
Autori
Korać, P ; Lasan-Trčić, R ; Dominis, M
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni
Izvornik
Acta Clinica Croatica
/ - , 2008, 52-53
Skup
19th Ljudevit Jurak International Symposium on comparative pathology
Mjesto i datum
Zagreb, Hrvatska, 06.05.2008. - 07.05.2008
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Nije recenziran
Ključne riječi
Trisomy 21; Fetus
Sažetak
Amniocentesis examination showed a female fetuswith trisomy 21 suggesting Down syndrome. After med-ical pregnancy termination, administrative mistake tookplace and the fetus was regarded as male. The onlymaterials left were the heart and femur stored in forma-lin. Amniocentesis results could only be confirmed by the available tissue examination. The heart was sub-mitted to formalin fixation and embedded in paraffinfollowing standard procedure. The femur needed to bedecalcinated for a longer period than standard bonemarrow trephine biopsy and then was submitted to for-malin fixation and embedded in paraffin. FISH tech-nique was performed on sections from both tissues us-ing probes for chromosomes X and Y, and a probe forchromosome 21. Results showed two signals that repre-sented X chromosome and three signals that represent-ed chromosome 21. The data suggested that final de- scription of the aborted fetus was an administrative mis-take indeed.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
108-0000000-0353 - Novi pristupi dijagnostici nasljednih bolesti (Begović, Davor, MZOS ) ( CroRIS)
108-1081873-1893 - Prognostički faktori, dijagnostika i terapija hemoblastoza (Jakšić, Branimir, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Zagreb