Pregled bibliografske jedinice broj: 408122
Antioxidant PBN ameliorates the teratogenic influence of 5-azacytidine in the rat
Antioxidant PBN ameliorates the teratogenic influence of 5-azacytidine in the rat // Conference papers of 20th Ljudevit Jurak International Symposium on Comparative Pathology
Zagreb, 2009. str. 15-15 (predavanje, međunarodna recenzija, sažetak, ostalo)
CROSBI ID: 408122 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Antioxidant PBN ameliorates the teratogenic influence of 5-azacytidine in the rat
Autori
Sobočan, Nikola ; Sinčić, Nino ; Katušić, Ana ; Šerman, Ljiljana ; Nikuševa-Martić, Tamara ; Jurić-Lekić, Gordana ; Paić, Frane ; Vlahović, Maja ; Bulić-Jakuš, Floriana
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo
Izvornik
Conference papers of 20th Ljudevit Jurak International Symposium on Comparative Pathology
/ - Zagreb, 2009, 15-15
Skup
20th Ljudevit Jurak International Symposium on Comparative Pathology
Mjesto i datum
Zagreb, Hrvatska, 05.06.2009. - 06.06.2009
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
PBN; 5-azacytidine; antioxidans; rat
Sažetak
Influence of the antioxidant N– tert– Butyl– α – phenylnitron (PBN) on teratogenesis induced by the DNA demethylating agent 5-azacytidine (5azaC) was investigated in the rat. Here we present data where PBN significantly improved most of developmental parameters when used as a pretreatment to 5azaC which can lead to conclusion that the teratogenic impact of 5azaC could at least partially depend on activation of oxidative stress pathways.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
108-1080399-0335 - Eksperimentalni embrionalni tumori i razvoj zametaka sisavaca in vitro i in vivo (Jakuš, Florijana, MZOS ) ( CroRIS)
108-1080399-0383 - Muški i ženski spolni sustav: razvoj, normalna histofiziologija i neplodnost (Ježek, Davor, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Zagreb
Profili:
Maja Vlahović
(autor)
Tamara Nikuševa Martić
(autor)
Gordana Jurić-Lekić
(autor)
Ljiljana Šerman
(autor)
Floriana Jakuš
(autor)
Nino Sinčić
(autor)
Ana Katušić Bojanac
(autor)
Frane Paić
(autor)