Naslov
Influence of body position on cerebrospinal and aqueous fluids pressures in cats

Autori
Klarica, Marijan ; Kuzman, Tomislav ; Mandac, Inga ; Radoš, Milan ; Orešković, Darko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Clinical Neurology and Neurosurgery / - , 2008, 38-38

Skup
Hydrocephalus 2008

Mjesto i datum
Hannover, Njemačka, 17.09.2008. - 20.09.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
body position; cerebrospinal fluid (CSF); aqueous fluid; pressure; cats

Sažetak
There are contradictory reports about correlation of intracranial (ICP) and intraocular pressure (IOP). ICP is measured invasively in patients with intracranial hypertension, while IOP is determined by less precise noninvasive methods. For this reason we compared ICP and IOP measured by invasive tehniques in cats during changes of body position. Experiments were performed on chloralose anaesthetized cats (n=10). Cannulae were introduced into lateral ventricle (LV), cortical (CSS) and lumbar (LSS) subarachnoid spaces, and in anterior ocular chamber of right eye. Intraural line was taken as reference zero pressure point. The animals and measuring instruments were fixed on board and pressures were measured in horizontal and vertical position. In horizontal position, pressure in the eye (IOP = 18.5 ± 0.6 cm H2O) and pressures in cerebrospinal fluid (LV = 17.4 ± 0.9 ; CSS = 17.2 ± 0.7 ; LSS = 17.8 ± 1.2 cm H2O) were similar. In vertical position, lumbar pressure increased (LSS = 33.5± 2.3 cm H2O), pressures in cranial cavity fell to subatmospheric value (LV = -4.1± 0.9 cm H2O ; CSS = -4.8± 0.5 cm H2O), while IOP showed small decrease (14.3± 0.1 cm H2O). It appears that a change in body position, from horizontal to vertical, causes drastic changes of pressures in different parts of cerebrospinal fluid system, while pressure change in ocular fluid is relatively small. Our results indicate that in animals without intracranial hypertension, the intraocular and intracranial pressures are not significantly interconnected.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

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