Naslov
Neural substrate of target detection in an MEG oddball study with faces

Autori
Sušac, Ana ; Ilmoniemi, Risto ; Ranken, Doug ; Supek, Selma

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Biomagnetism: Transdisciplinary Research and Exploration / Kakigi, K ; Yokosawa, K ; Kuriki, S. - Sapporo : Hokkaido University Press, 2008, 134-136

ISBN
978-4-8329-0355-5

Skup
16th International conference on biomagnetism BIOMAG 2008

Mjesto i datum
Sapporo, Japan, 25.08.2008. - 29.08.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
MEG; multi-start downhill simplex method; face processing; oddball paradigm; target detection

Sažetak
Detection of a rare target stimulus among frequent standard stimuli elicits the electric P300 component and its magnetic counterpart. The aim of this study was to identify the neural pathway of a target-related response in an oddball paradigm with faces. Measurements were carried out at the BioMag Laboratory using a 306-channel whole-head magnetometer (Elekta Neuromag Ltd., Helsinki). MEG data were analyzed assuming multiple current dipoles in a sphere model and using the Cortical Start Spatio-Temporal (CSST) inverse procedure incorporated in the MRIVIEW software. The earliest sources identified for standards and targets had distinct locations and dynamics. Sources active around 170 ms did not considerably differ for standards and targets except that target stimuli evoked additional frontal activity in some subjects. However, in the later time interval of 250– 320 ms, a strong target-related activity was evident and frontal activation was found for all subjects despite rather large intersubject differences in cortical activations in other regions. The activity in the anterior regions was followed by the activation in the parietal cortex at 320– 420 ms. The identified fronto-parietal network might represent a neural correlate of target detection.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Temeljne medicinske znanosti

POVEZANOST RADA