Pregled bibliografske jedinice broj: 398409
Serotonin transporter gene polymorphisms in Crohn's disease patients
Serotonin transporter gene polymorphisms in Crohn's disease patients // Abstracts/Journal of Crohn's and Colitis 2009 Vol 3:S113 (Abst.P258)
Hamburg, 2009. (poster, međunarodna recenzija, sažetak, stručni)
CROSBI ID: 398409 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Serotonin transporter gene polymorphisms in Crohn's disease patients
Autori
Grubelić Ravić, Katja ; Čuković Čavka, Silvija ; Anzulović, Dora ; Brinar, Marko ; Krznarić, Željko ; Sertić, Jadranka ; Božina, Nada ; Rojnić Kuzman, Martina ; Vucelić, Boris
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni
Izvornik
Abstracts/Journal of Crohn's and Colitis 2009 Vol 3:S113 (Abst.P258)
/ - Hamburg, 2009
Skup
4th Congress of ECCO
Mjesto i datum
Hamburg, Njemačka, 05.02.2009. - 07.02.2009
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
serotonin transporter gene polymorphisms; Crohn disease
Sažetak
Serotonin (5-HT) is an important factor in gut function, playing key roles in intestinal peristalsis, secretion, vasodilatation and sensory signalling. The serotoninselective reuptake transporter protein (SERT) terminates the action of 5-HT. Human SERT is encoded by a single gene on chromosome 17q11 ; two important polymorphic sites in the SERT gene are: variable number tandem repeats in the gene’ s second intron (SERTin2), and an insertion/deletion in the promoter region (SERTPR). Consistent with the effects of 5-HT in the gut, SERT polymorphisms could potentially be involved in the development of IBD. The aim of this study was to evaluate the possible role of SERT polymorphisms in pathogenesis of CD.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
108-1081874-1917 - Upalne bolesti crijeva (Crohnova bolest i ulcerozni kolitis) (Vucelić, Boris, MZOS ) ( CroRIS)
Ustanove:
Klinički bolnički centar Zagreb
Profili:
Boris Vucelić
(autor)
Silvija Čuković-Čavka
(autor)
Nada Božina
(autor)
Dora Grgić
(autor)
Martina Rojnić Kuzman
(autor)
Željko Krznarić
(autor)
Jadranka Sertić
(autor)
Marko Brinar
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus