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Pregled bibliografske jedinice broj: 395223

Successful treatment of diffuse large B-cell non-Hodgkin lymphoma with modified CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy and rituximab in a patient with Nijmegen syndrome


Dumić, Miroslav; Radman-Livaja, Ivo; Krnić, Nevena; Nola, Marin; Kušec, Rajko; Begović, Davor; Labar, Boris; Radoš, Marko
Successful treatment of diffuse large B-cell non-Hodgkin lymphoma with modified CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy and rituximab in a patient with Nijmegen syndrome // Clinical Lymphoma & Myeloma, 7 (2007), 9; 590-593 (međunarodna recenzija, kratko priopcenje, znanstveni)


CROSBI ID: 395223 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Successful treatment of diffuse large B-cell non-Hodgkin lymphoma with modified CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy and rituximab in a patient with Nijmegen syndrome

Autori
Dumić, Miroslav ; Radman-Livaja, Ivo ; Krnić, Nevena ; Nola, Marin ; Kušec, Rajko ; Begović, Davor ; Labar, Boris ; Radoš, Marko

Izvornik
Clinical Lymphoma & Myeloma (1557-9190) 7 (2007), 9; 590-593

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
Nijmegen syndrome; diffuse large B-cell non-Hodgkin lymphoma; chemotherapy; rituximab

Sažetak
A 17-year-old Croatian boy with Nijmegen breakage syndrome (NBS) who developed diffuse large B-cell non-Hodgkin lymphoma is presented. The majority of the patients with this rare autosomal recessive disease are of Slavic origin and, in most of them, the disease is caused by NBS1 mutation 657de15, as was found in our patient. Nijmegen breakage syndrome is characterized by microcephaly, growth retardation, abnormal facial appearance, spontaneous chromosomal rearrangements, immunodeficiency, and a high predisposition to cancer development, predominantly lymphoma. Because of increased sensitivity to radiation therapy and chemotherapy, the treatment of malignancies in patients with NBS can be difficult. To our knowledge, our patient is the first with NBS reported in the literature who was successfully treated for diffuse large B-cell lymphoma with the anti-CD20 monoclonal antibody rituximab in addition to a modified dose of CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy. He has been in complete remission for 3 years after finishing the treatment

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
108-0000000-0353 - Novi pristupi dijagnostici nasljednih bolesti (Begović, Davor, MZOS ) ( CroRIS)
108-0000000-0359 - Nasljedne endokrine bolesti u djece (Dumić, Miroslav, MZOS ) ( CroRIS)
108-1081872-1913 - LEUKEMIJE I TRANSPLANTACIJA KRVOTVORNIH MATIČNIH STANICA (Duraković, Nadira, MZOS ) ( CroRIS)
108-1980955-3094 - Genetika i funkcija hematopoeze i mikrookoliša Ph- mijeloproliferativnih bolesti (Kušec, Rajko, MZOS ) ( CroRIS)

Ustanove:
Medicinski fakultet, Zagreb,
Klinička bolnica "Dubrava",
Klinički bolnički centar Zagreb

Profili:

Avatar Url Boris Labar (autor)

Avatar Url Marko Radoš (autor)

Avatar Url Miroslav Dumić (autor)

Avatar Url Davor Begović (autor)

Avatar Url Ivo Radman-Livaja (autor)

Avatar Url Marin Nola (autor)

Avatar Url Rajko Kušec (autor)


Citiraj ovu publikaciju:

Dumić, Miroslav; Radman-Livaja, Ivo; Krnić, Nevena; Nola, Marin; Kušec, Rajko; Begović, Davor; Labar, Boris; Radoš, Marko
Successful treatment of diffuse large B-cell non-Hodgkin lymphoma with modified CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy and rituximab in a patient with Nijmegen syndrome // Clinical Lymphoma & Myeloma, 7 (2007), 9; 590-593 (međunarodna recenzija, kratko priopcenje, znanstveni)
Dumić, M., Radman-Livaja, I., Krnić, N., Nola, M., Kušec, R., Begović, D., Labar, B. & Radoš, M. (2007) Successful treatment of diffuse large B-cell non-Hodgkin lymphoma with modified CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy and rituximab in a patient with Nijmegen syndrome. Clinical Lymphoma & Myeloma, 7 (9), 590-593.
@article{article, author = {Dumi\'{c}, Miroslav and Radman-Livaja, Ivo and Krni\'{c}, Nevena and Nola, Marin and Ku\v{s}ec, Rajko and Begovi\'{c}, Davor and Labar, Boris and Rado\v{s}, Marko}, year = {2007}, pages = {590-593}, keywords = {Nijmegen syndrome, diffuse large B-cell non-Hodgkin lymphoma, chemotherapy, rituximab}, journal = {Clinical Lymphoma and Myeloma}, volume = {7}, number = {9}, issn = {1557-9190}, title = {Successful treatment of diffuse large B-cell non-Hodgkin lymphoma with modified CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy and rituximab in a patient with Nijmegen syndrome}, keyword = {Nijmegen syndrome, diffuse large B-cell non-Hodgkin lymphoma, chemotherapy, rituximab} }
@article{article, author = {Dumi\'{c}, Miroslav and Radman-Livaja, Ivo and Krni\'{c}, Nevena and Nola, Marin and Ku\v{s}ec, Rajko and Begovi\'{c}, Davor and Labar, Boris and Rado\v{s}, Marko}, year = {2007}, pages = {590-593}, keywords = {Nijmegen syndrome, diffuse large B-cell non-Hodgkin lymphoma, chemotherapy, rituximab}, journal = {Clinical Lymphoma and Myeloma}, volume = {7}, number = {9}, issn = {1557-9190}, title = {Successful treatment of diffuse large B-cell non-Hodgkin lymphoma with modified CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy and rituximab in a patient with Nijmegen syndrome}, keyword = {Nijmegen syndrome, diffuse large B-cell non-Hodgkin lymphoma, chemotherapy, rituximab} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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