Naslov
New Horizons for the Subplate Zone and Its Pioneering Neurons

Autori
Ayoub, E. Albert ; Kostović, Ivica ;

Izvornik
Cerebral Cortex (1047-3211) 19 (2009), 8; 1705-1707

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
evolution; gene chip; neocortex; subplate zone; synaptogenesis

Sažetak
Transitional neuronal layers are a hallmark of the prenatal and neonatal brain yet their contribution to the development of higher functions is not clear. Evidence accumulated over the last 3 decades shows that early connectivity and functional activity start in a transitional layer called the subplate zone (SPZ). The SPZ is host to a heterogenous population of neurons and its evolutionary complexity peaked in the human brain. In this issue of Cerebral Cortex, three reports (Hoerder-Suabedissen et al., 2008 ; McKellar and Shatz, 2008 ; Moore et al., 2008) present new data and evidence in three species (mouse, rat, human) as to the function of the SPZ, to the heterogenity of its cellular composition, and to the genetic basis of its development.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA