Pregled bibliografske jedinice broj: 39230
The effect of peptidoglycan monomer on cytikine profile of T cell responses to ovalbumin in mice
The effect of peptidoglycan monomer on cytikine profile of T cell responses to ovalbumin in mice // Fourth International forum on global vaccinology; Abstracts / Kurstak, Edouard (ur.).
Dubrovnik, 1999. str. W2-4 (predavanje, međunarodna recenzija, sažetak, znanstveni)
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Naslov
The effect of peptidoglycan monomer on cytikine profile of T cell responses to ovalbumin in mice
Autori
Špoljar, Beata ; Hanzl-Dujmović, Ivana ; Šantak, Maja ; Tomašić, Jelka
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Fourth International forum on global vaccinology; Abstracts
/ Kurstak, Edouard - Dubrovnik, 1999, W2-4
Skup
Fourth Internationa Forum on Global Vaccinology
Mjesto i datum
Dubrovnik, Hrvatska, 30.09.1999. - 03.10.1999
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
peptidoglycan monomer; cytokine profile; gamma-interferon; IL-4
Sažetak
Peptidoglycan monomer(PGM)originating from Brevibacterium divaricatum possess immunomodulating properties. We have shown recently that humoral immune response to ovalbumin (OVA in mice could be potentiated several fold after s.c. administration of PGM mixed with OVA. In this study the T cell response activation was monitored as secretion of IL-4 and IFN gamma from lymph node lymphocytes of immunized mice. The production of these cytokines was upregulated in immunized mice treated with PGM. PGM stimulates both Th1 and Th2 like immune responses.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
