Naslov
Assessing glycemia in type 1 diabetic patients using mycrodialysis continuous glucose monitoring system

Autori
Radman, Maja ; Eržen Jurišić, Dubravka ; Ljutić, Dragan ; Jerković, Romana ; Kovačić, Nataša ; Hozo, Izet

Izvornik
Annals of Saudi medicine (0256-4947) 27 (2007), 3; 166-170

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
aspart; NPH; glargine; GlucoDay

Sažetak
Background: Microdialysis continuous glucose monitor (GlucoDay) provides assessment of blood glucose dynamics. Patients and Methods: In 52 type 1 diabetics on two times/day NPH and pre-meal aspart insulin randomized in two groups: the continuation of NPH (n = 26), or once daily glargine (n = 26), 48-h GlucoDay registrations were started on the beginnig and after 4 months of the following. Results: At baseline, time spent in the euglycemic range (glucose between 3.9 and 8.0 mmol/l) was for the NPH group 37.96 ± ; 6.81% and 35.83 ± ; 6.24% for the glargine group. At end point, time in the euglycemic range increased in both groups (51.02 ± ; 7.22% versus 57.29 ± ; 10.27%). Time spent in the hypoglycemic range (glucose below 3.9 mmol/l) was 9.98 ± ; 2.57% for the first group, and 10.24 ± ; 3.55% for the second group at baseline. At end point, time in the hypoglycemic range decreased in both groups (8.00 ± ; 2.13% versus 6.59 ± ; 2.04%). Conclusion: The analysis of the GlucoDay data gave us other informations about glycemia than hemoglobin A1c and self-monitoring of blood glucose, such us peakless activity profile and the lower percentage time spent in the hypoglycemic range in the glargine treated group.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA