Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 388123

In Croatians type I psoriasis is associated with Cw*0602-B57-DRB1*0701-DQA1*0201-DQB1*0201 extended haplotype


Kaštelan, Marija; Čečuk-Jeličić, Esma; Grubić, Zorana; Gruber, Franjo; Prpić, Larisa; Simonić, Edita; Kaštelan, Andrija
In Croatians type I psoriasis is associated with Cw*0602-B57-DRB1*0701-DQA1*0201-DQB1*0201 extended haplotype // 11th Congress of European Academy of Dermatology and Venereology
Prag, Češka Republika, 2002. (poster, međunarodna recenzija, sažetak, znanstveni)


CROSBI ID: 388123 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
In Croatians type I psoriasis is associated with Cw*0602-B57-DRB1*0701-DQA1*0201-DQB1*0201 extended haplotype

Autori
Kaštelan, Marija ; Čečuk-Jeličić, Esma ; Grubić, Zorana ; Gruber, Franjo ; Prpić, Larisa ; Simonić, Edita ; Kaštelan, Andrija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
11th Congress of European Academy of Dermatology and Venereology

Mjesto i datum
Prag, Češka Republika, 02.10.2002. - 06.10.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Psoriasis; Croatia; Extended haplotype
(psoriasis; Croatia; extended haplotype)

Sažetak
AIM: Analysis of the polymorphism of HLA class II alleles and the Caucasian extended haplotype Cw*0602-B57-DRB1*0701-DQA1*0201-DQB1*0201 in type I and type II psoriasis in the Croatian population. PATIENTS AND METHODS: Seventy-seven unrelated patients with chronic stable psoriasis from the Department of Dermatology University Hospital Rijeka were grouped to type I and type II psoriasis according to the anamnestic data. Analysis of HLA class II alleles were performed by PCR method using sequence specific oligonucleotide probes. RESULTS: Patients with type I psoriasis (early onset, positive family history) showed significant association with DRB1*0701  relative risk (RR) = 5.83 , DQA1*0201 (RR=6.12), DQB1*0201 (RR=3.29) and DQB1*0303 alleles (RR=7.51). Type II psoriatics (late onset, no family history) did not show association with any class II alleles. In type I patients we found significant increase of the Caucasian extended haplotype Cw*0602-B57-DRB1*0701-DQA1*0201-DQB1*0201 in comparison to controls (RR=7.72). This haplotype was not detected in any type II psoriatics. CONCLUSIONS: Type I psoriasis is associated with Cw*0602-B57-DRB1*0701-DQA1*0201-DQB1*0201 extended haplotype in Croatians. Furthermore, DRB1*0701, DQA1*0201, DQB1*0201 and DQB1*0303 alleles carry the highest risk for developing type I psoriasis in our population.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Rijeka,
Klinički bolnički centar Rijeka


Citiraj ovu publikaciju:

Kaštelan, Marija; Čečuk-Jeličić, Esma; Grubić, Zorana; Gruber, Franjo; Prpić, Larisa; Simonić, Edita; Kaštelan, Andrija
In Croatians type I psoriasis is associated with Cw*0602-B57-DRB1*0701-DQA1*0201-DQB1*0201 extended haplotype // 11th Congress of European Academy of Dermatology and Venereology
Prag, Češka Republika, 2002. (poster, međunarodna recenzija, sažetak, znanstveni)
Kaštelan, M., Čečuk-Jeličić, E., Grubić, Z., Gruber, F., Prpić, L., Simonić, E. & Kaštelan, A. (2002) In Croatians type I psoriasis is associated with Cw*0602-B57-DRB1*0701-DQA1*0201-DQB1*0201 extended haplotype. U: 11th Congress of European Academy of Dermatology and Venereology.
@article{article, author = {Ka\v{s}telan, Marija and \v{C}e\v{c}uk-Jeli\v{c}i\'{c}, Esma and Grubi\'{c}, Zorana and Gruber, Franjo and Prpi\'{c}, Larisa and Simoni\'{c}, Edita and Ka\v{s}telan, Andrija}, year = {2002}, keywords = {Psoriasis, Croatia, Extended haplotype}, title = {In Croatians type I psoriasis is associated with Cw\ast0602-B57-DRB1\ast0701-DQA1\ast0201-DQB1\ast0201 extended haplotype}, keyword = {Psoriasis, Croatia, Extended haplotype}, publisherplace = {Prag, \v{C}e\v{s}ka Republika} }
@article{article, author = {Ka\v{s}telan, Marija and \v{C}e\v{c}uk-Jeli\v{c}i\'{c}, Esma and Grubi\'{c}, Zorana and Gruber, Franjo and Prpi\'{c}, Larisa and Simoni\'{c}, Edita and Ka\v{s}telan, Andrija}, year = {2002}, keywords = {psoriasis, Croatia, extended haplotype}, title = {In Croatians type I psoriasis is associated with Cw\ast0602-B57-DRB1\ast0701-DQA1\ast0201-DQB1\ast0201 extended haplotype}, keyword = {psoriasis, Croatia, extended haplotype}, publisherplace = {Prag, \v{C}e\v{s}ka Republika} }




Contrast
Increase Font
Decrease Font
Dyslexic Font