Pregled bibliografske jedinice broj: 385963
Subcutaneous dirofilariasis caused by Dirofilaria repens diagnosed by histopathologic and polymerase chain reaction analysis
Subcutaneous dirofilariasis caused by Dirofilaria repens diagnosed by histopathologic and polymerase chain reaction analysis // Acta dermatovenerologica Croatica, 16 (2008), 4; 222-225 (recenziran, članak, stručni)
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Naslov
Subcutaneous dirofilariasis caused by Dirofilaria
repens diagnosed by histopathologic and polymerase
chain reaction analysis
Autori
Marušić, Zlatko ; Stastny, Tomislav ; Kirac, Iva ; Stojčević, Dagny ; Krušlin, Božo ; Tomas, Davor
Izvornik
Acta dermatovenerologica Croatica (1330-027X) 16
(2008), 4;
222-225
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni
Ključne riječi
subcutaneous dirofilariasis ; caused by Dirofilaria ; diagnosed by histopathologic and polymerase chain reaction
Sažetak
A 31-year-old man with a history of intravenous drug abuse presented with an inflamed subcutaneous nodule in his left thigh. The nodule measured up to 1.2 cm in largest diameter. Under the clinical impression of an inflamed epidermal cyst or a subcutaneous abscess, surgical excision was performed. Histopathologic examination of the nodule and subsequent polymerase chain reaction (PCR) analysis revealed the presence of the helminth Dirofilaria (D.) repens, a member of the family Filarioidea. Dirofilariasis is a parasitosis caused by D. repens and D. immitis that most frequently affects canines. It can rarely be found in humans, usually in the form of a subcutaneous nodule. In Europe, most cases of human dirofilariasis have been detected in the Mediterranean countries, Ukraine and Russia, but sporadic cases have also been reported in central and north European countries. Dirofilariasis must be distinguished from other forms of filarial disease such as onchocercosis and Wuchereria bancrofti filariasis. Diagnosing dirofilariasis purely by histopathology has its pitfalls, especially when the morphology of the nematode is altered due to inflammatory response or surgical artifacts. PCR analysis offers an opportunity to confirm dirofilariasis and identify the dirofilarial species as well. Briefly, we conclude that a diagnosis of subcutaneous dirofilariasis should be considered in cases of subcutaneous mass in an endemic area of animal dirofilariasis.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Veterinarska medicina
POVEZANOST RADA
Projekti:
MZOS-108-0000000-3489 - ODREĐIVANJE NAJRACIONALNIJE TERAPIJE EHINOKOKOZE (Stojčević, Dagny, MZOS ) ( CroRIS)
MZOS-108-1081870-1884 - Razvojna neuropatologija genetskih malformacija moždane kore čovjeka (Krušlin, Božo, MZOS ) ( CroRIS)
MZOS-134-0000000-3381 - Promjene bubrežne arterije u bolesnika s karcinomom bubrega (Čupić, Hrvoje, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
Opća županijska bolnica Požega
Profili:
Zlatko Marušić
(autor)
Dagny Stojčević Jan
(autor)
Davor Tomas
(autor)
Božo Krušlin
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- EMBASE (Excerpta Medica)
- MEDLINE