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Pregled bibliografske jedinice broj: 385276

Recombinant factor VIIa in treatment of severe thrombocytopenic patients - Our experience


Balen, Sanja; Roganović, J.; Vukelić-Damiani, Nada
Recombinant factor VIIa in treatment of severe thrombocytopenic patients - Our experience // Vox sanguinis Vol. 89 Supplement 1 / Abstracts / Alice Maniatis, PhD, Athens Greece ; Irene Kontopoulou-Griva, MD, Athens, Greece ; Paul Strengers, MD, Amsterdam, the Netherlands (ur.).
Atena: Basil Blackwell, 2005. str. 195-195 (poster, nije recenziran, sažetak, znanstveni)


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Naslov
Recombinant factor VIIa in treatment of severe thrombocytopenic patients - Our experience

Autori
Balen, Sanja ; Roganović, J. ; Vukelić-Damiani, Nada

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Vox sanguinis Vol. 89 Supplement 1 / Abstracts / Alice Maniatis, PhD, Athens Greece ; Irene Kontopoulou-Griva, MD, Athens, Greece ; Paul Strengers, MD, Amsterdam, the Netherlands - Atena : Basil Blackwell, 2005, 195-195

Skup
XVth Regional Congress of the International Society of Blood Transfusion, Europe, Athens, Greece 2-6 July, 2005

Mjesto i datum
Atena, Grčka, 02.07.2005. - 06.07.2005

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Recombinant factor VIIa; severe thrombocytopenic patients

Sažetak
A 17-year old girl with chronic immunothrombocytopenia was admitted to the Hematooncologic Unit of the Department of Internal Medicine, Clinical Hospital Center Rijeka, due to ongoing headaches and nausea going on for two days prior to admittance. At admittance she developed terminal neck stiffness without focal neurological disturbances (seizures) and with numerous petechiae and hematomas all over the body. Laboratory findings: Tr 1 E 4.57 Hb 134 Hct 0.38 ; coagulation tests: APTT 32s PTT 0.86 fibrinogen 4.35 AT III 110. Brain CT scan and MRI detected right parieto-occipital and left supratentorial subaracnoidal bleeding. Therapy consisted of intravenous immunoglobulin administration (IVIg 1 g/kg for two days), high doses of glucocorticoids (metilprednisolon 1 g/d intravenously for 3 days), platelet transfusion (5 doses every 6 hours, a total of 50 doses), with recombinant factor VIIa (NovoSeven NovoNordisk 90 µ g/kg every 2-4 hours, a total of 8 x 4.8 mg) and other supportive and symptomatic measures. After three days of treatment neurological findings improved, the control brain MRI was without signs of progression. Laboratory findings: Tr 35 ; coagulation test: APTT 26s PTT 1.52 fibrinogen 2.51. The patient was urgently transferred to the Ljubljana Clinical Center for laparoscopic splenectomy. Our experience confirms the importance of recombinant factor VIIa application in thrombocytopenic patients with sever bleeding.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Klinički bolnički centar Rijeka

Citiraj ovu publikaciju:

Balen, Sanja; Roganović, J.; Vukelić-Damiani, Nada
Recombinant factor VIIa in treatment of severe thrombocytopenic patients - Our experience // Vox sanguinis Vol. 89 Supplement 1 / Abstracts / Alice Maniatis, PhD, Athens Greece ; Irene Kontopoulou-Griva, MD, Athens, Greece ; Paul Strengers, MD, Amsterdam, the Netherlands (ur.).
Atena: Basil Blackwell, 2005. str. 195-195 (poster, nije recenziran, sažetak, znanstveni)
Balen, S., Roganović, J. & Vukelić-Damiani, N. (2005) Recombinant factor VIIa in treatment of severe thrombocytopenic patients - Our experience. U: Alice Maniatis, PhD, Athens Greece, Irene Kontopoulou-Griva, MD, Athens, Greece & Paul Strengers, MD, Amsterdam, the Netherlands (ur.)Vox sanguinis Vol. 89 Supplement 1 / Abstracts.
@article{article, author = {Balen, Sanja and Roganovi\'{c}, J. and Vukeli\'{c}-Damiani, Nada}, year = {2005}, pages = {195-195}, keywords = {Recombinant factor VIIa, severe thrombocytopenic patients}, title = {Recombinant factor VIIa in treatment of severe thrombocytopenic patients - Our experience}, keyword = {Recombinant factor VIIa, severe thrombocytopenic patients}, publisher = {Basil Blackwell}, publisherplace = {Atena, Gr\v{c}ka} }
@article{article, author = {Balen, Sanja and Roganovi\'{c}, J. and Vukeli\'{c}-Damiani, Nada}, year = {2005}, pages = {195-195}, keywords = {Recombinant factor VIIa, severe thrombocytopenic patients}, title = {Recombinant factor VIIa in treatment of severe thrombocytopenic patients - Our experience}, keyword = {Recombinant factor VIIa, severe thrombocytopenic patients}, publisher = {Basil Blackwell}, publisherplace = {Atena, Gr\v{c}ka} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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