Naslov
Antioxidant therapy in experimental spinal cord trauma

Autori
Pantović, Radojka ; Eraković, Vesna ; Draganić, Pero

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 47th International Conference on the Bioscience of Lipids, Metabolism and function of lipids in the brain ; u: Chemistry and Physics of Lipids 143 (2006) (1/2) / - , 2006, 95-95

Skup
International Conference on the Bioscience of Lipids, Metabolism and function of lipids in the brain (47 ; 2006)

Mjesto i datum
Pečuh, Mađarska, 05.09.2006. - 09.09.2006

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
free fatty acids; ascorbic acid; HBOT

Sažetak
In this experiment we followed the effect of ascorbic acid, a naturally occurring free radical scavenger, and the effect of hyperbaric oxygenation, a potent inhibitor of tissue hypoxia, as well as the effect produced by combining these therapeutical approaches on the level of palmitic (C16:0), stearic (C18:0), oleic (C18:1), arachidonic (C20:4) and docosahexaenoic (C22:6) acids in an experimental model of a spinal cord injury (SCI) in rabbits. The level of all analysed free fatty acids was increased in the spinal cord of experimental animals after neurotrauma. Treatment with ascorbic acid and hyperbaric oxygenation, as well as the combinations of hyperbaric oxygenation with the ascorbic acid resulted in a significant decrease of the level of the analysed FFAs, caused by neurotrauma.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Temeljne medicinske znanosti

POVEZANOST RADA