Pregled bibliografske jedinice broj: 382103
Effect of valproic acid on 5-hydroxytryptamine turnover in mouse brain
Effect of valproic acid on 5-hydroxytryptamine turnover in mouse brain // Journal of Pharmacy and Pharmacology, 37 (1985), 3; 199-200 doi:10.1111/j.2042-7158.1985.tb05040.x (međunarodna recenzija, vijest, znanstveni)
CROSBI ID: 382103 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Effect of valproic acid on 5-hydroxytryptamine turnover in mouse brain
Autori
Whitton, P. S. ; Orešković, Darko ; Jernej, Branimir ; Bulat, Marin
Izvornik
Journal of Pharmacy and Pharmacology (0022-3573) 37
(1985), 3;
199-200
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, vijest, znanstveni
Ključne riječi
valproic acid ; 5-HT ; 5-HIAA ; mouse brain
Sažetak
The effect of the antiepileptic drug valproic acid (di-n-propylacetic acid, 200 mg kg-1) on brain 5-hydroxytryptamine (5-HT) synthesis during monoamine oxidase inhibition by pargyline hydrochloride (120 mg kg-1) was studied in mice. Valproic acid increased 5-HT synthesis and elevated 5-hydroxyindoleacetic acid level in brain indicating that turnover of 5-HT is increased. The possible significance of this effect in relation to anticonvulsant action of valproic acid is discussed.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
