Pregled bibliografske jedinice broj: 371527
Mjerenje apsorbirane doze zračenja i oštećenja DNK pri RTG pregledu pluća kod djece
Mjerenje apsorbirane doze zračenja i oštećenja DNK pri RTG pregledu pluća kod djece // Zbornik radova sedmog simpozija Hrvatskog društva za zaštitu od zračenja = Proceedings of the seventh Symposium of the Croatian Radiation Protection Association / Barišić, Delko ; Grahek, Željko ; Krajcar Bronić, Ines ; Miljanić, Saveta (ur.).
Zagreb: Hrvatsko društvo za zaštitu od zračenja, 2008. str. 111-117 (predavanje, nije recenziran, cjeloviti rad (in extenso), znanstveni)
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Naslov
Mjerenje apsorbirane doze zračenja i oštećenja DNK pri RTG pregledu pluća kod djece
(Dose Determination and DNA damage in X-ray diagnostic of children)
Autori
Milković, Đurđica ; Garaj-Vrhovac, Vera ; Ranogajec-Komor, Maria ; Miljanić, Saveta ; Beck, Natko ; Gajski, Goran ; Knežević, Željka
Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni
Izvornik
Zbornik radova sedmog simpozija Hrvatskog društva za zaštitu od zračenja = Proceedings of the seventh Symposium of the Croatian Radiation Protection Association
/ Barišić, Delko ; Grahek, Željko ; Krajcar Bronić, Ines ; Miljanić, Saveta - Zagreb : Hrvatsko društvo za zaštitu od zračenja, 2008, 111-117
ISBN
978-953-96133-6-3
Skup
Sedmi simpozij Hrvatskog društva za zaštitu od zračenja
Mjesto i datum
Opatija, Hrvatska, 29.05.2008. - 31.05.2008
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Nije recenziran
Ključne riječi
RTG pregleda pluća; Apsorbirana doza; RPL; TLD; Komet test;
(X-ray examinations; absorbed dose; TLD; Radiophotoluminescent (RPL) dosimetry; Comet Assay; DNA damage)
Sažetak
The knowledge of absorbed dose in tissues is important in radiological department especially in paediatrics to estimate the risk of radiation exposure. In addition the risk of genome damage can also be estimated by using several cytogenetic techniques. In this paper comet assay was chosen as suitable technique for assessment of DNA damage induced by ionising radiation of chest radiogram. The aim of this study was to correlate the data on the cytogenetic status of children caused by X-ray examinations of chest with the exposure dose. To compare these data to the dose of exposure determined with thermoluminescence (TL) dosimetry and the radiophotoluminescent (RPL) glass dosimetry system, teen children with pulmonary diseases, ages between 4 and 14 years were assessed. Samples of peripheral blood were collected from patients before and after X-ray examination and Comet Assay were carried out under alkaline conditions using tail length as a measure of DNA damage. The differences between the mean values of tail length for Comet assay before (13.71± ; 0.60) and after (14.51± ; 0.81) exposure were statistically significant (P<0.05, ANOVA). The correlation between doses in the primary beam (measured on the back of children patients) and the ratio of tail lengths (DNA damage) after and before irradiation was found. The doses measured with TL and RPL dosimeters show an agreement satisfactory for X-ray diagnostics and are suitable for dosimetric measurements in X-ray diagnostic.
Izvorni jezik
Hrvatski
Znanstvena područja
Fizika, Kemija, Biologija
POVEZANOST RADA
Projekti:
022-0222148-2125 - Mutageni i antimutageni u ekogenetičkim istraživanjima (Garaj-Vrhovac, Vera, MZOS ) ( CroRIS)
098-0982904-2954 - Fizičko-kemijski učinci ionizirajućih zračenja u materijalima (Mihaljević, Branka, MZOS ) ( CroRIS)
277-2770966-0962 - Učinci radioloških dijagnostičkih postupaka pri pregledu dišnih putova u djece (Milković, Đurđica, MZOS ) ( CroRIS)
Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Dječja bolnica Srebrnjak
Profili:
Željka Knežević Medija
(autor)
Saveta Miljanić
(autor)
Vera Garaj-Vrhovac
(autor)
Ferencne Ranogajec
(autor)
Natko Beck
(autor)
Goran Gajski
(autor)
Đurđica Milković
(autor)