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Pregled bibliografske jedinice broj: 369209

Life-threatening Valproate Overdose Successfully Treated with Haemodialysis


Meštrović, Julije; Filipović, Tomislav; Polić, Branka; Stričević, Luka; Omazić, Ante; Kuzmanić-Šamija, Radenka; Markić, Joško
Life-threatening Valproate Overdose Successfully Treated with Haemodialysis // Arhiv za higijenu rada i toksikologiju, 59 (2008), 4; 295-298 doi:10.2478/10004-1254-59-2008-1884 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 369209 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Life-threatening Valproate Overdose Successfully Treated with Haemodialysis

Autori
Meštrović, Julije ; Filipović, Tomislav ; Polić, Branka ; Stričević, Luka ; Omazić, Ante ; Kuzmanić-Šamija, Radenka ; Markić, Joško

Izvornik
Arhiv za higijenu rada i toksikologiju (0004-1254) 59 (2008), 4; 295-298

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
central nervous system depressants; intensive care; thrombocytopenia; toxicity

Sažetak
Valproate (VPA) poisoning is an increasing clinical problem. The most common finding in VPA overdose is the depression of the central nervous system, which may progress to coma and death. This type of poisoning is difficult to treat, as no antidote exists. This report describes a case with a 16-year-old girl who poisoned herself with valproate. Initial treatment included naloxone, but she did not respond. She became comatose, with serum VPA concentration of 1320 µ ; ; g mL-1. Three sessions of haemodialysis were performed, effectively eliminating VPA and decreasing the serum concentration. The patient regained consciousness and fully recovered. To our knowledge, this is the highest serum VPA concentration reported by now in children aged 16 or less. Haemodialysis has proved to be the treatment of choice for life-threatening acute VPA overdose in children.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
216-0000000-3391 - Djeca s posebnim zdravstvenim potrebama (Meštrović, Julije, MZOS ) ( CroRIS)

Ustanove:
KBC Split,
Medicinski fakultet, Split

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada doi Hrčak

Citiraj ovu publikaciju:

Meštrović, Julije; Filipović, Tomislav; Polić, Branka; Stričević, Luka; Omazić, Ante; Kuzmanić-Šamija, Radenka; Markić, Joško
Life-threatening Valproate Overdose Successfully Treated with Haemodialysis // Arhiv za higijenu rada i toksikologiju, 59 (2008), 4; 295-298 doi:10.2478/10004-1254-59-2008-1884 (međunarodna recenzija, članak, znanstveni)
Meštrović, J., Filipović, T., Polić, B., Stričević, L., Omazić, A., Kuzmanić-Šamija, R. & Markić, J. (2008) Life-threatening Valproate Overdose Successfully Treated with Haemodialysis. Arhiv za higijenu rada i toksikologiju, 59 (4), 295-298 doi:10.2478/10004-1254-59-2008-1884.
@article{article, author = {Me\v{s}trovi\'{c}, Julije and Filipovi\'{c}, Tomislav and Poli\'{c}, Branka and Stri\v{c}evi\'{c}, Luka and Omazi\'{c}, Ante and Kuzmani\'{c}-\v{S}amija, Radenka and Marki\'{c}, Jo\v{s}ko}, year = {2008}, pages = {295-298}, DOI = {10.2478/10004-1254-59-2008-1884}, keywords = {central nervous system depressants, intensive care, thrombocytopenia, toxicity}, journal = {Arhiv za higijenu rada i toksikologiju}, doi = {10.2478/10004-1254-59-2008-1884}, volume = {59}, number = {4}, issn = {0004-1254}, title = {Life-threatening Valproate Overdose Successfully Treated with Haemodialysis}, keyword = {central nervous system depressants, intensive care, thrombocytopenia, toxicity} }
@article{article, author = {Me\v{s}trovi\'{c}, Julije and Filipovi\'{c}, Tomislav and Poli\'{c}, Branka and Stri\v{c}evi\'{c}, Luka and Omazi\'{c}, Ante and Kuzmani\'{c}-\v{S}amija, Radenka and Marki\'{c}, Jo\v{s}ko}, year = {2008}, pages = {295-298}, DOI = {10.2478/10004-1254-59-2008-1884}, keywords = {central nervous system depressants, intensive care, thrombocytopenia, toxicity}, journal = {Arhiv za higijenu rada i toksikologiju}, doi = {10.2478/10004-1254-59-2008-1884}, volume = {59}, number = {4}, issn = {0004-1254}, title = {Life-threatening Valproate Overdose Successfully Treated with Haemodialysis}, keyword = {central nervous system depressants, intensive care, thrombocytopenia, toxicity} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka::


  • Analytical Abstracts
  • BIOSIS Previews (Biological Abstracts)
  • CANCERLIT
  • CA Search (Chemical Abstracts)
  • MEDLINE
  • Pollution Abstracts
  • Water Resources Abstracts


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