Naslov
Crystal and molecular structure of novel ferrocene bioconjugate with potential antimicrobial activity

Autori
Cetina, Mario ; Nagl, Ante ; Lapić, Jasmina ; Đaković, Senka ; Rapić, Vladimir

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Book of Proceedings of the 4th International Textile, Clothing & Design Conference / Dragčević, Zvonko - Zagreb : Tekstilno-tehnološki fakultet Sveučilišta u Zagrebu, 2008, 323-328

ISBN
978-953-7105-26-6

Skup
4th International Textile, Clothing & Design Conference

Mjesto i datum
Dubrovnik, Hrvatska, 05.10.2008. - 08.10.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
nosocomial infections ; bioorganometallic chemistry ; ferrocene bioconjugate ; antimicrobial activity ; hydrogen bonds ; Pi...Pi interactions

Sažetak
Textile materials provide basic requirements for bacterial growth and multiplication. Hospital materials are especially known to be major sources of cross-infection, and therefore, the hospital textiles that have potential biocidal properties would help reduce an important source of microorganisms involved in infections. One of the classes of antimicrobial agents for textiles constitutes organometallic compounds. The novel ferrocene bioconjugate with potential antimicrobial activity was prepared and its crystal structure has been determined by X-ray structure analysis. The compound crystallized in monoclinic space group P 2_1/c. The conformation of the cyclopentadienyl rings is almost halfway between eclipsed and staggered, as the C1– Cg1– Cg2– C9 torsion angle is 159.71(13)^o. The rings are nearly parallel, with the corresponding dihedral angle of 2.68(10)^o. The C11=O1 and C17=O5 carbonyl groups are slightly twisted out from the plane of the Cp rings to which they are attached [dihedral angles are 9.01(12)^o and 4.22(12)^o, respectively]. The N– H… O and C– H… O hydrogen bonds and weak aromatic Pi… Pi interactions link the molecules into two-dimensional framework.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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