Transcranial sonography (TCS) in the diagnosis of essential tremor and Parkinson&#8217; s disease

Bošnjak, Jelena; Budišić, Mislav; Lovrenčić-Huzjan, Arijana; Vuković, Vlasta; Bene, Raphael; Trkanjec, Zlatko; Demarin, Vida

Pregled bibliografske jedinice broj: 367041

Transcranial sonography (TCS) in the diagnosis of essential tremor and Parkinson’ s disease

Bošnjak, Jelena; Budišić, Mislav; Lovrenčić-Huzjan, Arijana; Vuković, Vlasta; Bene, Raphael; Trkanjec, Zlatko; Demarin, Vida

Transcranial sonography (TCS) in the diagnosis of essential tremor and Parkinson’ s disease // European Journal of Neurology, Vol.15, Suppl.3 / Lenzi, Gian Luigi ; Gil-Nagel, Antonio (ur.).
Madrid, Španjolska: Wiley-Blackwell, 2008. str. 95-95 (poster, međunarodna recenzija, sažetak, znanstveni)

CROSBI ID: 367041 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Transcranial sonography (TCS) in the diagnosis of essential tremor and Parkinson’ s disease

Autori
Bošnjak, Jelena ; Budišić, Mislav ; Lovrenčić-Huzjan, Arijana ; Vuković, Vlasta ; Bene, Raphael ; Trkanjec, Zlatko ; Demarin, Vida

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
European Journal of Neurology, Vol.15, Suppl.3 / Lenzi, Gian Luigi ; Gil-Nagel, Antonio - : Wiley-Blackwell, 2008, 95-95

Skup
12th Congress of the European Federation of Neurological Societies

Mjesto i datum
Madrid, Španjolska, 23.08.2008. - 26.08.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
transcranial sonography; TCS; movement disorder; Parkinson's disease; essential tremor

Sažetak
Background and aims: Clinical examination of well-established symptoms is still the most accurate way to diagnose Parkinson’ s disease (PD) and essential tremor (ET). However, the misdiagnosis rates for PD and ET in the early stages is as high as 20– 30% in PD and about 30% in ET. The aim of this study is to assess the usefulness of transcranial sonography (TCS) in the evaluation of patients with ET and PD. Methods: Our study was performed on 190 individuals, including 30 patients with ET, 80 PD patients, and 80 matched controls. TCS was applied by standardized protocol: SN was displayed, encircled, and measured twice. Mean area was calculated. The Mann-Whitney U-test was used for statistical inter-group comparison. Results: In the control group and PD group, bilateral combined mean SN size was 0.17 cm2 (&plusmn ; 0.07) and 0.27 cm2 (&plusmn ; 0.06), with statistically significant difference (p<0.001). The mean SN size in patients with ET was 0.15 cm2 (&plusmn ; 0.04), (for the right side 0.15 cm2 (&plusmn ; 0.04) and 0.16 cm2 (&plusmn ; 0.05) for the left side), which was significantly different from PD group (p<0.001), but not from the control group (p=0.240). Conclusions: Specific finding of SN hyperechogenicity in PD can help to distinguish ET from PD in doubtful clinical cases or in the early stages of the disease when symptoms might overlap. TCS is a practical and valuable neuroimaging tool in diagnosis of ET and PD.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA

Projekti:
134-1340036-0033 - Uloga genetskih markera u razvoju cerebralne aterosklerotske bolesti (Demarin, Vida, MZOS ) ( CroRIS)
134-1340036-0034 - Funkcijska dijagnostika moždane cirkulacije (Lovrenčić-Huzjan, Arijana, MZOS ) ( CroRIS)
134-1340036-0035 - Uloga vaskularnih čimbenika rizika u patogenezi Alzheimerove bolesti (Trkanjec, Zlatko, MZOS ) ( CroRIS)

Ustanove:
KBC "Sestre Milosrdnice"

Profili:

Mislav Budišić (autor)