Naslov
The impact of the less invasive treatment on the outcome of the patients with brain abscess

Autori
Pangerčić, Ana ; Chudy, Darko ; Heinrich, Zdravko ; Miklić, Pavle ; Baršić, Bruno

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Abstracts of the 5th Congress of the Croatian Neurosurgical Society and the Joint Meeting with Congress of Neurological Surgeons ; u: Neurologica Croatica. Supplement 57 (2008) / Rotim, Krešimir ; Beroš, Vili - Zagreb, 2008, 163-163

Skup
Congress of the Croatian Neurosurgical Society and the Joint Meeting with Congress of Neurological Surgeons (5 ; 2008)

Mjesto i datum
Dubrovnik, Hrvatska, 02.09.2008. - 05.09.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
brain abscess; antibiotics; stereotactic aspiration

Sažetak
To evaluate the efficacy of the less-invasive treatment (combination antibiotics with/without stereotactic aspiration) compared to radical (the classical surgery and antibiotics) in the treatment of the brain abscess(es). Over the period of 7 years (2000.-2007.) 74 patients were retrospectively identified as having brain abscess at Hospital for Infectious disease. To compare efficacy of treatment patients were divided into two groups: less invasive treatment (30 patients) and radical treatment (44 patients). Unfavourable outcome (GOS=<4) was assessed in 45 patients. In less-invasive treatment it was observed in 19(63.3%) patients, in radical group in 26(59.1%) patients. Death as a final outcome was registered in 9 patients (30.0%) in less-invasive group and in 6(13.6%) patients in radical group. Univariate analysis showed that the presence of the focal neurological deficits on admission was significantly associated with unfavourable outcome (OR= 4.81, 95% CI 1.44-18.52, p=0. 014) as well as lower GCS (OR per unit decrease =2.42, 95% CI 1.34-4.35, p=0. 002). The choice of neurosurgical procedure did not have impact on the outcome of treatment (OR=1.34, 95% CI 0.41-4.65, p=0.628). Multivariate logistic regression analysis showed that declining of GCS was the only variable independently associated with death (OR per unit decrease=1.11, 95%CI 1.07-1.17, p<0. 001). Therapeutic outcomes of the brain abscess did not differ when less invasive and radical treatment were compared despite the tendency that less invasive treatment was associated with worse survival. The presence of the focal neurological deficit on admission as well as GCS was associated with poorer outcome.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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