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Pregled bibliografske jedinice broj: 366177

Enhanced antitumor activity of irinotecan combined with propolis and its polyphenolic compounds on Ehrlich ascites tumor in mice

Benković, Vesna; Horvat Knežević, Atika; Brozović, Gordana; Knežević, Fabijan; Đikić, Domagoj; Bevanda, Milenko; Bašić, Ivan; Oršolić Nada
Enhanced antitumor activity of irinotecan combined with propolis and its polyphenolic compounds on Ehrlich ascites tumor in mice // Biomedicine and Pharmacotherapy, 61 (2007), 5; 292-297 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 366177 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Enhanced antitumor activity of irinotecan combined with propolis and its polyphenolic compounds on Ehrlich ascites tumor in mice

Autori
Benković, Vesna ; Horvat Knežević, Atika ; Brozović, Gordana ; Knežević, Fabijan ; Đikić, Domagoj ; Bevanda, Milenko ; Bašić, Ivan ; Oršolić Nada

Izvornik
Biomedicine and Pharmacotherapy (0753-3322) 61 (2007), 5; 292-297

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Ehrlich ascites tumor; propolis; flavonoids; irinotecan; tumor growth

Sažetak
Effects of anticancer drug irinotecan combined with ethanolic extract of propolis (EEP), water-soluble derivate of propolis (WSDP), quercetin, or naringin on the growth of Ehrlich ascites tumor (EAT) and life span of tumor bearing Swiss albino mice were studied. Test components were given to mice intraperitoneally (ip) at dose of 100 mg kg-1 for three consecutive days before the ip injection of EAT cells (1x106). Irinotecan was administered ip at dose of 50 mg kg-1 on days 1, 13, and 19 after tumor cell inoculation. The results clearly demonstrate the synergistic action of irinotecan and EEP on survival time. These results suggest the benefits of potential clinical trials using propolis preparation EEP combined with irinotecan in order to maximize antitumor activity and potentially minimize postchemotherapeutic deteriorating reaction of cytostatic drug.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA

Projekti:
119-0000000-1255 - Kemoprevencija rasta tumora polifenolnim sastavnicama (Oršolić, Nada, MZOS ) ( CroRIS)
119-0532265-1254 - Imunoadjuvantno i zaštitno djelovanje propolisa u životinja (Benković, Vesna, MZOS ) ( CroRIS)

Ustanove:
Prirodoslovno-matematički fakultet, Zagreb

Profili:

Avatar Url Nada Oršolić (autor)

Avatar Url Fabijan Knežević (autor)

Avatar Url Gordana Brozović (autor)

Avatar Url Domagoj Đikić (autor)

Avatar Url Ivan Bašić (autor)

Avatar Url Vesna Benković (autor)

Citiraj ovu publikaciju:

Benković, Vesna; Horvat Knežević, Atika; Brozović, Gordana; Knežević, Fabijan; Đikić, Domagoj; Bevanda, Milenko; Bašić, Ivan; Oršolić Nada
Enhanced antitumor activity of irinotecan combined with propolis and its polyphenolic compounds on Ehrlich ascites tumor in mice // Biomedicine and Pharmacotherapy, 61 (2007), 5; 292-297 (međunarodna recenzija, članak, znanstveni)
Benković, V., Horvat Knežević, A., Brozović, G., Knežević, F., Đikić, D., Bevanda, M., Bašić, I. & Oršolić Nada (2007) Enhanced antitumor activity of irinotecan combined with propolis and its polyphenolic compounds on Ehrlich ascites tumor in mice. Biomedicine and Pharmacotherapy, 61 (5), 292-297.
@article{article, author = {Benkovi\'{c}, Vesna and Horvat Kne\v{z}evi\'{c}, Atika and Brozovi\'{c}, Gordana and Kne\v{z}evi\'{c}, Fabijan and \DJiki\'{c}, Domagoj and Bevanda, Milenko and Ba\v{s}i\'{c}, Ivan}, year = {2007}, pages = {292-297}, keywords = {Ehrlich ascites tumor, propolis, flavonoids, irinotecan, tumor growth}, journal = {Biomedicine and Pharmacotherapy}, volume = {61}, number = {5}, issn = {0753-3322}, title = {Enhanced antitumor activity of irinotecan combined with propolis and its polyphenolic compounds on Ehrlich ascites tumor in mice}, keyword = {Ehrlich ascites tumor, propolis, flavonoids, irinotecan, tumor growth} }
@article{article, author = {Benkovi\'{c}, Vesna and Horvat Kne\v{z}evi\'{c}, Atika and Brozovi\'{c}, Gordana and Kne\v{z}evi\'{c}, Fabijan and \DJiki\'{c}, Domagoj and Bevanda, Milenko and Ba\v{s}i\'{c}, Ivan}, year = {2007}, pages = {292-297}, keywords = {Ehrlich ascites tumor, propolis, flavonoids, irinotecan, tumor growth}, journal = {Biomedicine and Pharmacotherapy}, volume = {61}, number = {5}, issn = {0753-3322}, title = {Enhanced antitumor activity of irinotecan combined with propolis and its polyphenolic compounds on Ehrlich ascites tumor in mice}, keyword = {Ehrlich ascites tumor, propolis, flavonoids, irinotecan, tumor growth} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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