{\rtf1\adeflang1025\ansi\ansicpg1250\uc1\adeff0\deff0\stshfdbch0\stshfloch0\stshfhich0\stshfbi0\deflang1050\deflangfe1050{\fonttbl{\f0\froman\fcharset238\fprq2{\*\panose 02020603050405020304}Times New Roman;}{\f2\fmodern\fcharset238\fprq1{\*\panose 02070309020205020404}Courier New;}{\f39\froman\fcharset0\fprq2 Times New Roman;}
{\f38\froman\fcharset204\fprq2 Times New Roman Cyr;}{\f40\froman\fcharset161\fprq2 Times New Roman Greek;}{\f41\froman\fcharset162\fprq2 Times New Roman Tur;}{\f42\fbidi \froman\fcharset177\fprq2 Times New Roman (Hebrew);}
{\f43\fbidi \froman\fcharset178\fprq2 Times New Roman (Arabic);}{\f44\froman\fcharset186\fprq2 Times New Roman Baltic;}{\f45\froman\fcharset163\fprq2 Times New Roman (Vietnamese);}{\f59\fmodern\fcharset0\fprq1 Courier New;}
{\f58\fmodern\fcharset204\fprq1 Courier New Cyr;}{\f60\fmodern\fcharset161\fprq1 Courier New Greek;}{\f61\fmodern\fcharset162\fprq1 Courier New Tur;}{\f62\fbidi \fmodern\fcharset177\fprq1 Courier New (Hebrew);}
{\f63\fbidi \fmodern\fcharset178\fprq1 Courier New (Arabic);}{\f64\fmodern\fcharset186\fprq1 Courier New Baltic;}{\f65\fmodern\fcharset163\fprq1 Courier New (Vietnamese);}}{\colortbl;\red0\green0\blue0;\red0\green0\blue255;\red0\green255\blue255;
\red0\green255\blue0;\red255\green0\blue255;\red255\green0\blue0;\red255\green255\blue0;\red255\green255\blue255;\red0\green0\blue128;\red0\green128\blue128;\red0\green128\blue0;\red128\green0\blue128;\red128\green0\blue0;\red128\green128\blue0;
\red128\green128\blue128;\red192\green192\blue192;}{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1033\langfe1050\cgrid\langnp1033\langfenp1050 
\snext0 Normal;}{\*\cs10 \additive \ssemihidden Default Paragraph Font;}{\*
\ts11\tsrowd\trftsWidthB3\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\trcbpat1\trcfpat1\tblind0\tblindtype3\tscellwidthfts0\tsvertalt\tsbrdrt\tsbrdrl\tsbrdrb\tsbrdrr\tsbrdrdgl\tsbrdrdgr\tsbrdrh\tsbrdrv 
\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang1024\langfe1024\cgrid\langnp1024\langfenp1024 \snext11 \ssemihidden Normal Table;}{\s15\ql \li0\ri0\widctlpar
\tx916\tx1832\tx2748\tx3664\tx4580\tx5496\tx6412\tx7328\tx8244\tx9160\tx10076\tx10992\tx11908\tx12824\tx13740\tx14656\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af2\afs20\alang1025 \ltrch\fcs0 
\f2\fs20\cf1\lang1050\langfe1050\cgrid\langnp1050\langfenp1050 \sbasedon0 \snext15 \styrsid2775102 HTML Preformatted;}}{\*\latentstyles\lsdstimax156\lsdlockeddef0}{\*\rsidtbl \rsid612137\rsid655738\rsid1003150\rsid1135574\rsid1391244\rsid2775102
\rsid4202979\rsid4260312\rsid5529882\rsid6513042\rsid9065095\rsid9371913\rsid10291226\rsid11037321\rsid11281537\rsid11624263\rsid12325421\rsid12399179\rsid12987968\rsid13648555\rsid14035102\rsid14642636\rsid14896042\rsid15933573}{\*\generator Microsoft Wo
rd 11.0.0000;}{\info{\title ALS AND FTLD:  COGNITIVE CHANGES AND GENETIC MARKERS}{\author Bo\'9eidar Li\'9a\'e8i\'e6}{\operator Bo\'9eidar Li\'9a\'e8i\'e6}{\creatim\yr2008\mo8\dy16\hr18\min1}{\revtim\yr2008\mo8\dy16\hr18\min2}
{\printim\yr2008\mo8\dy16\hr17\min55}{\version3}{\edmins1}{\nofpages1}{\nofwords467}{\nofchars2665}{\*\company Bo\'9eidar Li\'9a\'e8i\'e6}{\nofcharsws3126}{\vern24613}{\*\password 00000000}}{\*\xmlnstbl {\xmlns1 http://schemas.microsoft.com/office/word/20
03/wordml}{\xmlns2 urn:schemas-microsoft-com:office:smarttags}}\paperw11906\paperh16838\margl1417\margr1417\margt1417\margb1417\gutter0\ltrsect 
\deftab708\widowctrl\ftnbj\aenddoc\hyphhotz425\donotembedsysfont1\donotembedlingdata0\grfdocevents0\validatexml1\showplaceholdtext0\ignoremixedcontent0\saveinvalidxml0\showxmlerrors1\noxlattoyen\expshrtn
\noultrlspc\dntblnsbdb\nospaceforul\formshade\horzdoc\dgmargin\dghspace180\dgvspace180\dghorigin1417\dgvorigin1417\dghshow1\dgvshow1
\jexpand\viewkind1\viewscale100\pgbrdrhead\pgbrdrfoot\splytwnine\ftnlytwnine\htmautsp\nolnhtadjtbl\useltbaln\alntblind\lytcalctblwd\lyttblrtgr\lnbrkrule\nobrkwrptbl\viewnobound1\snaptogridincell\allowfieldendsel
\wrppunct\asianbrkrule\rsidroot12987968\newtblstyruls\nogrowautofit \fet0{\*\wgrffmtfilter 013f}\ilfomacatclnup0\ltrpar \sectd \ltrsect\linex0\headery708\footery708\colsx708\endnhere\sectlinegrid360\sectdefaultcl\sftnbj {\*\pnseclvl1
\pnucrm\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl2\pnucltr\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl3\pndec\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl4\pnlcltr\pnstart1\pnindent720\pnhang {\pntxta )}}{\*\pnseclvl5
\pndec\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl6\pnlcltr\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl7\pnlcrm\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl8\pnlcltr\pnstart1\pnindent720\pnhang 
{\pntxtb (}{\pntxta )}}{\*\pnseclvl9\pnlcrm\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}\pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid9371913 \rtlch\fcs1 \af0\afs24\alang1025 
\ltrch\fcs0 \fs24\lang1033\langfe1050\cgrid\langnp1033\langfenp1050 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12987968\charrsid1391244 ALS AND FTLD:  COGNITIVE CHANGES AND GENETIC MARKERS
\par }\pard \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid6513042 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12987968\charrsid1391244 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \ul\insrsid12987968\charrsid1391244 Rajka M. Li\'9a\'e8i\'e6
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12987968\charrsid1391244 Institute for Medical Research and Occupational Health, {\*\xmlopen\xmlns2{\factoidname place}}{\*\xmlopen\xmlns2{\factoidname City}}Zagreb{\*\xmlclose}, {\*\xmlopen\xmlns2{\factoidname 
country-region}}Croatia{\*\xmlclose}{\*\xmlclose}
\par 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid14035102\charrsid1391244 Background}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14035102\charrsid1391244 : }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12325421\charrsid1391244 A}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14035102\charrsid1391244 myotrophic }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11624263\charrsid1391244 l}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14035102\charrsid1391244 ateral }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11624263\charrsid1391244 s}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14035102\charrsid1391244 clerosis (A}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12325421\charrsid1391244 LS}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14035102\charrsid1391244 )}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid11624263\charrsid1391244  may be accompanied by cognitive impairment; when present it is mainly in the form of frontotemporal impairment.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12325421\charrsid1391244  }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14035102\charrsid1391244 Frontotemporal lobar degeneration (FTLD) is }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11624263\charrsid1391244 a focal, non-Alzheimer form of dementia, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14035102\charrsid1391244 
clinically characterized as either beha}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15933573\charrsid1391244 vioral or aphasic variants [1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14035102\charrsid1391244 ]. }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid12325421\charrsid1391244 The overlap between dementia and ALS is demonstrated by the presence of cognitive}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5529882\charrsid1391244 
, behavioral, executive dysfunction and change of personality in up to 50% of ALS patients}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11624263\charrsid1391244  [2]. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5529882\charrsid1391244 
Behavioral features are mostly due to changes in }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11037321\charrsid1391244 serotonergic and }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5529882\charrsid1391244 catecholaminergic system}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid11624263\charrsid1391244  [3}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15933573\charrsid1391244 ].}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5529882\charrsid1391244 
\par 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid655738\charrsid1391244 Objective: }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 To identify genetic correlates of cognitive changes with the emphasis on executive function in ALS patients. 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5529882\charrsid1391244 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid655738\charrsid1391244 Materials and methods}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 
: In a prospective study, two tests of executive functions (Controlled oral word association - FAS test; Tower of {\*\xmlopen\xmlns2{\factoidname City}}{\*\xmlopen\xmlns2{\factoidname place}}London{\*\xmlclose}{\*\xmlclose} (TOL)}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid612137\charrsid1391244 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244  were applied on 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11624263\charrsid1391244 6}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244  A
LS patients (}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11624263\charrsid1391244 10}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244  male, 60.5\'b15.8 years), as defined by El Escorial Criteria. }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid10291226\charrsid1391244 All subjects also completed the Dementia Rating Scale II (DRS}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1391244\charrsid1391244 -}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10291226\charrsid1391244 II). }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid655738\charrsid1391244 -1021 C/T polymorphism of DBH gene, 102 C/T polymorphism of 5-HT2A receptor gene, val}{\rtlch\fcs1 \af0 \ltrch\fcs0 \super\insrsid655738\charrsid1391244 66}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid655738\charrsid1391244 met polymorphism of COMT gene and val}{\rtlch\fcs1 \af0 \ltrch\fcs0 \super\insrsid655738\charrsid1391244 158/108}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 
met polymorphism of BDNF gene were correlated with a cognitive tests}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1135574\charrsid1391244 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5529882\charrsid1391244 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid655738\charrsid1391244 Results: }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 ALS patients carrying {\*\xmlopen\xmlns2{\factoidname City}}{\*\xmlopen\xmlns2{\factoidname place}}GG{\*\xmlclose}, 
{\*\xmlopen\xmlns2{\factoidname State}}GA{\*\xmlclose}{\*\xmlclose} and AA genotype of the BDNF gene polymorphism were 73%, 20% and 7%, respectively. The frequency of {\*\xmlopen\xmlns2{\factoidname City}}{\*\xmlopen\xmlns2{\factoidname place}}GG
{\*\xmlclose}, {\*\xmlopen\xmlns2{\factoidname State}}GA{\*\xmlclose}{\*\xmlclose}, AA genotype for COMT g
ene polymorphism was 33%, 53% and 14%, respectively. The DBH gene polymorphism distribution was 47%, 47% and 6% for CC, CT and TT genotype, respectively. The frequency of CC, CT, TT genotype for 5-HT2A gene polymorphism was 30%, 60% and 10%, respectively.
 57% of patients showed deficient word generation capability. 21% }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11624263\charrsid1391244 of patients }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 were impaired on TOL Total move score and 33% }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid612137\charrsid1391244 of patients }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 on TOL Total rules violation score. 40% }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid612137\charrsid1391244 of patients }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 were impaired at DRS II Conceptualization subtest and 20% }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid612137\charrsid1391244 of patients }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 
on DRS-II Memory subtest. No significant (p>0.05) relationship between genes polymorphism and variables of executive functional tests was found}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14896042\charrsid1391244  [4]}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid655738\charrsid1391244 . 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5529882\charrsid1391244 
\par }\pard\plain \ltrpar\s15\ql \li0\ri0\widctlpar\tx916\tx1832\tx2748\tx3664\tx4580\tx5496\tx6412\tx7328\tx8244\tx9160\tx10076\tx10992\tx11908\tx12824\tx13740\tx14656\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid6513042 \rtlch\fcs1 
\af2\afs20\alang1025 \ltrch\fcs0 \f2\fs20\cf1\lang1050\langfe1050\cgrid\langnp1050\langfenp1050 {\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\f0\fs24\lang1033\langfe1050\langnp1033\insrsid655738\charrsid1391244 Conclusion: }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\lang1033\langfe1050\langnp1033\insrsid655738\charrsid1391244 The preliminary findings }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\lang1033\langfe1050\langnp1033\insrsid9065095\charrsid1391244 reveal }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\lang1033\langfe1050\langnp1033\insrsid11624263\charrsid1391244 a tendency for executive deficit in ALS. }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\lang1033\langfe1050\langnp1033\insrsid9065095\charrsid1391244 There is a p}{\rtlch\fcs1 
\af0\afs24 \ltrch\fcs0 \f0\fs24\lang1033\langfe1050\langnp1033\insrsid14035102\charrsid1391244 otential genotype-specific influence in ALS for executive function}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\lang1033\langfe1050\langnp1033\insrsid9065095\charrsid1391244 s}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\lang1033\langfe1050\langnp1033\insrsid14035102\charrsid1391244 . }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\lang1033\langfe1050\langnp1033\insrsid655738\charrsid1391244 Further studies on a larger sample, however, are needed in order to}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\lang1033\langfe1050\langnp1033\insrsid15933573\charrsid1391244  }{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\lang1033\langfe1050\langnp1033\insrsid655738\charrsid1391244 confirm it.
\par }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\lang1033\langfe1050\langnp1033\insrsid5529882\charrsid1391244 
\par }\pard\plain \ltrpar\ql \fi-1440\li1440\ri0\widctlpar\tqr\tx360\tqr\tx540\tx720\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin1440\itap0\pararsid6513042 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1033\langfe1050\cgrid\langnp1033\langfenp1050 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid12325421\charrsid1391244 References:
\par }\pard \ltrpar\ql \li0\ri0\widctlpar\tqr\tx0\tqr\tx540\tx720\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid6513042 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15933573\charrsid1391244 1. }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid12325421\charrsid1391244 McKhann GM, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid5529882\charrsid1391244 et al}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5529882\charrsid1391244 . Cli}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12325421\charrsid1391244 
nical and pathological diagnosis of frontotemporal dementia:}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1003150\charrsid1391244  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12325421\charrsid1391244 report of the Work Group on Frontotemporal Dementia and Pick
{\*\xmlopen\xmlns2{\factoidname PersonName}}'{\*\xmlclose}s Disease. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid12325421\charrsid1391244 Arch Neurol}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12325421\charrsid1391244  2001; }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid12325421\charrsid1391244 58}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12325421\charrsid1391244 : 1803-9.
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11624263\charrsid1391244 2. Loman-Hoerth C, et al. The overlap of amyotrophic lateral sclerosis and frontotemporal dementia. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid11624263\charrsid1391244 Neurology}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid11624263\charrsid1391244  2002; }{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid11624263\charrsid1391244 59}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11624263\charrsid1391244 : 1077-9.
\par 3}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15933573\charrsid1391244 . Huey ED, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid15933573\charrsid1391244 et al}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15933573\charrsid1391244 . A systematic review of
 neurotransmitter deficits and treatments in frontotemporal dementia.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid15933573\charrsid1391244  Neurology }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15933573\charrsid1391244 2006; }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid15933573\charrsid1391244 66}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15933573\charrsid1391244 : 17-22 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12325421\charrsid1391244 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14896042\charrsid1391244 4}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15933573\charrsid1391244 . }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 Liscic RM, }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\i\insrsid5529882\charrsid1391244 et al.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid655738\charrsid1391244  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 
Cognitive changes and genetic markers in amyotrophic lateral sclerosis: Preliminary results of a prospective study. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid4260312\charrsid1391244 6}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\super\insrsid4260312\charrsid1391244 th
}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid4260312\charrsid1391244  International Conference on Frontotemporal Dementias,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4260312\charrsid1391244  Rotterdam }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 
2008}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1135574\charrsid1391244  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid655738\charrsid1391244 (}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1003150\charrsid1391244 P-097}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid655738\charrsid1391244 ). }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12987968\charrsid1391244 
\par }}