Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 365752

Caspase 3 immunohistochemical expression in borderline and invasive serous ovarian tumours


Čarić, Ana; Poljičanin, Ana; Košta, Vana; Prović, Ivana; Tomić, Snježana; Vilović, Katarina
Caspase 3 immunohistochemical expression in borderline and invasive serous ovarian tumours // Abstracts of the 16th Euroconference on Apoptosis and 5th Swiss Apoptosis Meeting
Bern, Švicarska, 2008. (poster, međunarodna recenzija, sažetak, ostalo)


CROSBI ID: 365752 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Caspase 3 immunohistochemical expression in borderline and invasive serous ovarian tumours

Autori
Čarić, Ana ; Poljičanin, Ana ; Košta, Vana ; Prović, Ivana ; Tomić, Snježana ; Vilović, Katarina

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Abstracts of the 16th Euroconference on Apoptosis and 5th Swiss Apoptosis Meeting / - , 2008

Skup
16th Euroconference on Apoptosis and 5th Swiss Apoptosis Meeting

Mjesto i datum
Bern, Švicarska, 06.09.2008. - 09.09.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
serous ovarian tumours; caspase 3; apoptosis

Sažetak
To demonstrate the immunohistochemical expression of caspase 3 in borderline and invasive serous ovarian tumours. We performed immunohistochemical staining of formalin fixed, paraffin-embedded tissue samples from 40 serous ovarian tumours, using caspase 3 monoclonal antibody, manufactured by R&D Systems (Minneapolis, USA). Apoptotic cells were detected by light microscopy (Olympus BX40). Immunohistochemical results were scored semiquantitatively. Tissue samples contained apoptotic cells with brown stained cytoplasm that were positive to active form of caspase 3. However considerable number of apoptotic cells did not show any caspase 3 positivity in both borderline and invasive serous ovarian tumours. Presence of caspase 3 negative apoptotic cells imply the possibility of activation of different apoptotic pathways in ovarian tumour cells. This implicates that in cancer therapy we should consider targeting divers molecules at the same time for the therapy to be successful.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
216-0000000-0479 - Uloga apoptoze u kancerogenezi ženskog spolnog sustava (Vilović, Katarina, MZOS ) ( CroRIS)
216-0000000-0484 - Dvostruki model ovarijalne kancerogeneze - molekularna i morfološka studija (Tomić, Snježana, MZOS ) ( CroRIS)

Ustanove:
Medicinski fakultet, Split


Citiraj ovu publikaciju:

Čarić, Ana; Poljičanin, Ana; Košta, Vana; Prović, Ivana; Tomić, Snježana; Vilović, Katarina
Caspase 3 immunohistochemical expression in borderline and invasive serous ovarian tumours // Abstracts of the 16th Euroconference on Apoptosis and 5th Swiss Apoptosis Meeting
Bern, Švicarska, 2008. (poster, međunarodna recenzija, sažetak, ostalo)
Čarić, A., Poljičanin, A., Košta, V., Prović, I., Tomić, S. & Vilović, K. (2008) Caspase 3 immunohistochemical expression in borderline and invasive serous ovarian tumours. U: Abstracts of the 16th Euroconference on Apoptosis and 5th Swiss Apoptosis Meeting.
@article{article, author = {\v{C}ari\'{c}, Ana and Polji\v{c}anin, Ana and Ko\v{s}ta, Vana and Provi\'{c}, Ivana and Tomi\'{c}, Snje\v{z}ana and Vilovi\'{c}, Katarina}, year = {2008}, keywords = {serous ovarian tumours, caspase 3, apoptosis}, title = {Caspase 3 immunohistochemical expression in borderline and invasive serous ovarian tumours}, keyword = {serous ovarian tumours, caspase 3, apoptosis}, publisherplace = {Bern, \v{S}vicarska} }
@article{article, author = {\v{C}ari\'{c}, Ana and Polji\v{c}anin, Ana and Ko\v{s}ta, Vana and Provi\'{c}, Ivana and Tomi\'{c}, Snje\v{z}ana and Vilovi\'{c}, Katarina}, year = {2008}, keywords = {serous ovarian tumours, caspase 3, apoptosis}, title = {Caspase 3 immunohistochemical expression in borderline and invasive serous ovarian tumours}, keyword = {serous ovarian tumours, caspase 3, apoptosis}, publisherplace = {Bern, \v{S}vicarska} }




Contrast
Increase Font
Decrease Font
Dyslexic Font