Pregled bibliografske jedinice broj: 363800
Macrolides with anti-inflammatory activity
Macrolides with anti-inflammatory activity
(2006)
CROSBI ID: 363800 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Macrolides with anti-inflammatory activity
Autori
Čulić, Ognjen ; Bosnar, Martina ; Marjanović, Nikola ; Jelić, Dubravko ; Alihodžić, Sulejman ; Vela, vanja ; Marušić Ištuk, Zorica ; Eraković, Vesna ; Bošnjak, Berislav ; Hrvačić, Boška ; Tomašković, Marija ; Munić, Vesna ; Ivetić, Vanesa ; Hutinec, Antun ; Kragol, Goran ; Leljak, Marija
Broj patenta
WO 20061087644 A2
Godina
2006
Datum patenta
24.08.2006.
Nositelj prava
Glaxosmithkline istraživački centar Zagreb d.o.o., ,
Sažetak
The present invention relates to novel semi-synthetic macrolides having anti-inflammatory activity. More particu-larly the invention relates to 14- and 15-membered macrolides substituted at 4"-position to their pharmaceutically acceptable derivatives, to processes and intermediates for their preparation, to pharmaceutical composition containing them and to their activity and use in the treatment of inflammatory diseases and conditions in humans and animals, especially those diseases associated 4 with excessive secretion of TNF-a, IL-1, IL-8, IL-2 or IL-5 ; and/or inhibitor of excessive lymphocyte proliferation ; and/or excessive granulocyte degranulation.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Fidelta d.o.o.
Profili:
Dubravko Jelić
(autor)
Nikola Marjanović
(autor)
Marija Tomašković
(autor)
Zorica Marušić Ištuk
(autor)
Ognjen Čulić
(autor)
Vanja Vela
(autor)
Martina Bosnar
(autor)
Goran Kragol
(autor)
Boška Hrvačić
(autor)
Antun Hutinec
(autor)
Vesna Munić Kos
(autor)
Berislav Bošnjak
(autor)
Vesna Eraković Haber
(autor)
Sulejman Alihodžić
(autor)