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Pregled bibliografske jedinice broj: 36318

Peptide-D : Molecular defining and possible functions.

Štambuk, Nikola; Pokrić, Biserka; Vikić-Topić, Dražen; Kazazić, Saša; Žarković, Neven; Konjevoda, Paško; Ćurković, Božidar; Babić-Naglić, Đurđa; Garaj-Vrhovac, Vera; Kopjar, Nevenka et al.
Peptide-D : Molecular defining and possible functions. // Abstracts of the 17th International and 13th European Congress of Clinical Chemistry and Laboratory Medicine ; u: Clinical Chemistry and Laboratory Medicine 37 (1999) (Spec.Suppl.) / Siest, G. (ur.).
Berlin: Walter de Gruyter, 1999. str. S84-S84 (predavanje, međunarodna recenzija, sažetak, znanstveni)

CROSBI ID: 36318 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Peptide-D : Molecular defining and possible functions.
(Peptide-D : Molecular defining and possible functions)

Autori
Štambuk, Nikola ; Pokrić, Biserka ; Vikić-Topić, Dražen ; Kazazić, Saša ; Žarković, Neven ; Konjevoda, Paško ; Ćurković, Božidar ; Babić-Naglić, Đurđa ; Garaj-Vrhovac, Vera ; Kopjar, Nevenka ; Užarević, Branka ; Stavljenić-Rukavina, Ana ; Trbojević-Čepe, Milica ; Ćurković, Tihomir.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 17th International and 13th European Congress of Clinical Chemistry and Laboratory Medicine ; u: Clinical Chemistry and Laboratory Medicine 37 (1999) (Spec.Suppl.) / Siest, G. - Berlin : Walter de Gruyter, 1999, S84-S84

Skup
International Congress of Clinical Chemistry and Laboratory Medicine (17 ; 1999) ; European Congress of Clinical Chemistry and Laboratory Medicine (13 ; 1999)

Mjesto i datum
Firenca, Italija, 06.06.1999. - 11.06.1999

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
peptide-D; Met-enkephalin; neuropeptides; calpain; calpastatin; autoimmune diseases

Sažetak
Peptide-D is a pentapeptide recently defined by means of SCA method. This peptide is involved in Ca2+ signalling in mammalian cells. We investigated Peptide-D and its complementary peptide (Met-enkephalin/Peptid-M) that belongs to the family of neuropeptides. The effects of the peptides on peripheral blood lymphocytes were analysed in vitro with respect to their influence on cell cycle, proliferation, apoptosis and mutagenesis. In vivo toxicity and cytoprotection were evaluated on the rat and mice model. Peptide-D and its complementary motif were analysed by one- and two-dimensional 1H and 13C NMR spectroscopy. Their fragmentation was followed by laser desorption mass spectroscopy. Spectroscopic findings and in vitro and in vivo studies contributed to the understanding of the physiologic and pathologic functions of the calpain-calpastatin system and related Met-enkephalin-FKB3 interactions. The results are discussed in the context of several ocular, nervous system and rheumatic diseases including: cataract, uveitis, optic neuritis, multiple sclerosis, Alzheimer's disease and rheumatoid arthritis.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Temeljne medicinske znanosti



POVEZANOST RADA

Projekti:
00980601
00980802
00981108
00981110

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Nikola Štambuk (autor)

Avatar Url Vera Garaj-Vrhovac (autor)

Avatar Url Ana Stavljenić (autor)

Avatar Url Paško Konjevoda (autor)

Avatar Url Dražen Vikić-Topić (autor)

Avatar Url Branka Užarević (autor)

Avatar Url Tihomir Ćurković (autor)

Avatar Url Neven Žarković (autor)

Avatar Url Saša Kazazić (autor)

Avatar Url Milica Trbojević-Čepe (autor)

Avatar Url Nevenka Kopjar (autor)

Avatar Url Biserka Pokrić (autor)

Avatar Url Božidar Ćurković (autor)

Citiraj ovu publikaciju:

Štambuk, Nikola; Pokrić, Biserka; Vikić-Topić, Dražen; Kazazić, Saša; Žarković, Neven; Konjevoda, Paško; Ćurković, Božidar; Babić-Naglić, Đurđa; Garaj-Vrhovac, Vera; Kopjar, Nevenka et al.
Peptide-D : Molecular defining and possible functions. // Abstracts of the 17th International and 13th European Congress of Clinical Chemistry and Laboratory Medicine ; u: Clinical Chemistry and Laboratory Medicine 37 (1999) (Spec.Suppl.) / Siest, G. (ur.).
Berlin: Walter de Gruyter, 1999. str. S84-S84 (predavanje, međunarodna recenzija, sažetak, znanstveni)
Štambuk, N., Pokrić, B., Vikić-Topić, D., Kazazić, S., Žarković, N., Konjevoda, P., Ćurković, B., Babić-Naglić, Đ., Garaj-Vrhovac, V. & Kopjar, N. (1999) Peptide-D : Molecular defining and possible functions.. U: Siest, G. (ur.)Abstracts of the 17th International and 13th European Congress of Clinical Chemistry and Laboratory Medicine ; u: Clinical Chemistry and Laboratory Medicine 37 (1999) (Spec.Suppl.).
@article{article, author = {\v{S}tambuk, Nikola and Pokri\'{c}, Biserka and Viki\'{c}-Topi\'{c}, Dra\v{z}en and Kazazi\'{c}, Sa\v{s}a and \v{Z}arkovi\'{c}, Neven and Konjevoda, Pa\v{s}ko and \'{C}urkovi\'{c}, Bo\v{z}idar and Babi\'{c}-Nagli\'{c}, \DJur\dja and Garaj-Vrhovac, Vera and Kopjar, Nevenka and U\v{z}arevi\'{c}, Branka and Stavljeni\'{c}-Rukavina, Ana and Trbojevi\'{c}-\v{C}epe, Milica and \'{C}urkovi\'{c}, Tihomir.}, editor = {Siest, G.}, year = {1999}, pages = {S84-S84}, keywords = {peptide-D, Met-enkephalin, neuropeptides, calpain, calpastatin, autoimmune diseases}, title = {Peptide-D : Molecular defining and possible functions.}, keyword = {peptide-D, Met-enkephalin, neuropeptides, calpain, calpastatin, autoimmune diseases}, publisher = {Walter de Gruyter}, publisherplace = {Firenca, Italija} }
@article{article, author = {\v{S}tambuk, Nikola and Pokri\'{c}, Biserka and Viki\'{c}-Topi\'{c}, Dra\v{z}en and Kazazi\'{c}, Sa\v{s}a and \v{Z}arkovi\'{c}, Neven and Konjevoda, Pa\v{s}ko and \'{C}urkovi\'{c}, Bo\v{z}idar and Babi\'{c}-Nagli\'{c}, \DJur\dja and Garaj-Vrhovac, Vera and Kopjar, Nevenka and U\v{z}arevi\'{c}, Branka and Stavljeni\'{c}-Rukavina, Ana and Trbojevi\'{c}-\v{C}epe, Milica and \'{C}urkovi\'{c}, Tihomir.}, editor = {Siest, G.}, year = {1999}, pages = {S84-S84}, keywords = {peptide-D, Met-enkephalin, neuropeptides, calpain, calpastatin, autoimmune diseases}, title = {Peptide-D : Molecular defining and possible functions}, keyword = {peptide-D, Met-enkephalin, neuropeptides, calpain, calpastatin, autoimmune diseases}, publisher = {Walter de Gruyter}, publisherplace = {Firenca, Italija} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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