Naslov
The difference between BIS guided vs. BIS unguided anesthesia in off pump coronary artery bypass grafting surgery

Autori
Karanović, Nenad ; Husedžinović I ; Nikić, N ; Carev, M ; Đogaš, Zoran ; Kardum, Goran ; Bradić N ; Desnica M ; Lojpur, Mihailo ; Jerčić, A ; Ujević, A.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Eur J Anaesthesiol 2007 ; 24 (Suppl 39): 17 / Basil, Matta - , 2007, 17-17

Skup
Annual Meeting of the European Society of Anaesthesiology Munich, Germany, June 9– 12, 2007

Mjesto i datum
München, Njemačka, 09.07.2007. - 12.07.2007

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
anesthesia; coronary artery bypass

Sažetak
Background and Goal of Study Clinical evaluation of BIS is still controversial (1). The aim was to find out the difference regarding amount of used anesthetic agents between BIS guided vs. BIS unguided anesthesia, during off pump coronary artery bypass grafting surgery (OPCABG). Materials and Methods After Medical Ethics Committee approval and written consent, patients scheduled for OPCABG surgery were randomly assigned into BIS (B) and control (C) groups. Excluding criteria: diabetes, liver and renal impairment, carotid circulatory insufficiency. In B group anesthesia was maintained according to BIS values at 40-45, whereas in C group according to anesthesiologist’ s estimation and experience. The total amounts of midazolam and fentanyl were compared at the end of anesthesia. End tidal sevoflurane (ETsevo) values were compared at 5 time points (S1-S5) according to particular surgery procedures. Ventilation was maintained with 50% oxygen in air, mean arterial pressure (MAP) between 70 and 85 mm Hg, heart rate between 60 and 90. The usage of other agents was registered. GLM for repeated measures, χ 2 and t tests were used for statistical analysis ; p<0.05 was considered statistically significant. Results and Discussions There was no difference between the groups regarding gender (p=0.31), age (p=0.77), body mass (p=0.34), body height (p=0.13), duration of anesthesia (p=0.70) and surgery (p=0.78). Agent B group (n=23) C group (n=25) p Fentanyl (mg) 1.66± ; ; 0.34 1.49± ; ; 0.26 0.060 Midazolam (mg) 38.04± ; ; 7.15 35.60± ; ; 9.50 0.320 ETsevo 1 (S1) 1.23± ; ; 0.34 1.06± ; ; 0.36 0.090 ETsevo 2 (S2) 1.31± ; ; 0.22 1.08± ; ; 0.25 0.001 ETsevo 3 (S3) 1.17± ; ; 0.19 1.25± ; ; 0.41 0.380 ETsevo 4 (S4) 1.10± ; ; 0.26 0.94± ; ; 0.24 0.030 ETsevo 5 (S5) 0.90± ; ; 0.18 0.80± ; ; 0.21 0.070 The significant difference existed among ETsevo values (F=21.6, p<0.001), as well as between B and C groups regarding repeated measures of ETsevo (F=3.3, p=0.012). Conclusion There was a significant difference in anesthesia for OPCABG surgery regarding ETsevo values guided by BIS vs. BIS unguided. Fentanyl appeared to be used more in group B than in group C.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA