Naslov
Diagnostic dellemas of FNAC of pilomatrixoma in head and neck

Autori
Trutin Ostović, Karmen ; Manojlović, Spomenka ; Štoos_Veić, Tajana ; Kaić, Gordana ; Virag, Mišo

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Knjiga sažetaka 3. hrvatskog kongresa kliničke citologije s međunarodnim sudjelovanjem / - , 2005, 187-187

Skup
3. hrvatski kongres kliničke citologije s međunarodnim sudjelovanjem

Mjesto i datum
Opatija, Hrvatska, 08.05.2005. - 11.05.2005

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
pilomatrixoma; cytology

Sažetak
BACKGROUND: Pilomatrixoma (calcifying epithelioma of Malherbe) is a rare skin appendage tumour. It is almost always benign and usually occurs in the first two decades of life. The most common sites are head and neck area or upper extremities. The fine needle aspiration cytology (FNAC) of pilomatrixoma frequently lead to a misdiagnosis of carcinoma. METHODS: Within four years we have performed fourteen FNA of pilomatrixoma out of which eight were located in head and neck. We used 25G needles attached to 20-ml disposable syringes. Smears were stained with Papanicolaou and Pappenheim staining methods. The cytological diagnoses were compared with the histological findings. RESULTS: There were 6 male and 2 female patients from 0.7 till 87 years old. Unequivocal benign diagnoses were rendered in six out of eight cases. In one case basal cell carcinoma could not be excluded (Fig.7). One case was misdiagnosed for squamous carcinoma (Fig. 9, 10). Diagnostic cytological features include cellular aspirates (Fig. 1, 2, 3). The smears consist of keratinized squamous and ghost cells (Fig. 1, 2, 4, 6, 11), multinucleated giant cells mainly associated with keratin fragments (Fig.1, 2, 5) and pink, fibrillary material enveloping clusters of small, basaloid epithelial cells (Fig. 3, 7). Basaloid cells may form rosettes and acini or appear isolated with high nuclear-cytoplasmic ratio (Fig. 8, 9), evenly dispersed chromatin, prominent nucleoli (Fig. 8, 9, 10) and nuclear moulding (Fig. 9, 10). Sometimes they are spindle (Fig. 12) and form trodimensional papillary formations (3, 8). CONCLUSION: The FNA cytological diagnosis of pilomatrixoma may be extremely difficult especially if there is a predominance of one component over the others. The FNA differential diagnosis of pilomatrixoma includes squamous cell, basal cell and Merkel cell carcinoma and various skin appendage and salivary gland tumours

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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