Naslov
Treatment with percutaneous ethanol injection (PEIT) of neck metastases in patients with thyroid cancer

Autori
Tomić Brzac, Hrvojka ; Kusačić Kuna, Sanja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Sixth International Congress of the Croatian Society of Nuclear Medicine : Book of Abstracts / - : Hrvatsko društvo za nuklearnu medicinu, 2008, 17-17

Skup
International Congress of the Croatian Society of Nuclear Medicine (6 ; 2008)

Mjesto i datum
Opatija, Hrvatska, 09.05.2008. - 12.05.2008

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
thyroid carcinoma; PEIT

Sažetak
At present time, a variety of techniques for percutaneous treatment of metastasis have been developed in intervention oncology (radiofrequency ablation, laser), but percutaneous injection of 95% ethanol (PEIT) under ultrasound guidance has been shown to be one of the simplest method. The objective of this study was to evaluate this technique for management of locally recurrent thyroid cancer in a group of patients with high risk of operative complications after repeated surgery and those who preferred not to have surgery. We treated 14 patients, 12 females and 2 males, average age 59 years (26-77) presented with solitary metastasis of thyroid cancer in the neck. All patients have undergone total thyroidectomy followed by radioiodine ablation of thyroid remnants. In five of patients a lateral neck dissection had been performed, and some of them had been operated several times because of reccurent disease. Three patients had distant metastases, and one patient had a second malignancy. The majority of patients had papillary carcinoma (12 of them) and 2 folliculary. PEIT was made in nodes previously confirmed as metastases by ultrasound guided fine needle aspiration biopsy (FNAB) and by thyreoglobulin in the aspirated material. The volume of ethanol used in treated nodes depends on their size. All treated patients were followed by ultrasound with Color Doppler, and serum thyroglobulin level was also reported. In the majority of patients, after one or more treatments, we noticed a reduction in the size of the metastatic nodule as well as decrease of thyroglobulin level. In three patients with a more widespread disease and metastases in the lungs and bones satisfactory results were not achieved. We conclude that PEIT is a satisfactory alternative treatment in patients with limited reccurrent neck metastases. The advantages of PEIT are its simplicity, less invasiveness, lower risk of complication, inexpensiveness, and ability to be repeated. Our first results, according to literature are encouraging. The method is well received by patients and surgery is always an option if the disease progresses.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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