Naslov
Stenotic occlusive lesions of internal carotid artery in diabetic patients

Autori
Vidjak, Vinko ; Hebrang, Andrija ; Brkljačić, Boris ; Barada, Ante, Brajša, Mladen ; Brnić, Zoran ; Novačić, Karlo ; Grga, Ante ; Hlevnjak, Dubravko ; Flegar-Meštrić, Zlata ; Vrhovski-Hebrang, Danijela

Izvornik
Collegium antropologicum (0350-6134) 31 (2007), 3; 775-780

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
internal carotid artery; diabetes mellitus; atherosclerotic lesions; digital subtraction angiography

Sažetak
Diabetes deteriorates atherosclerotic changes in the arteries. The aim of the study was to assess the prevalence and localization of stenotic atherosclerotic lesions of the internal carotid artery (ICA) in patients with diabetes. A prospective analysis of angiography findings was carried out in 150 diabetic and 150 non-diabetic patients with symptoms of cerebral ischemia using double-blind angiogram readings by two independent investigators. The degree of stenosis was determined using the North American Symptomatic Carotid Endartectomy Trial (NASCET) criteria. Stenoses of the proximal arterial segment accounted for the majority of extracranial ICA Stenoses, being more frequent in diabetic (left ICA 50, 7 %, right ICA 58, 0 %) than in the non-diabetic patients (left ICA 29, 3 %, right ICA 32, 7 %). Diabetic patients revealed a more significant rate of unilateral tandem ICA stenoses (14, 0-21, 3 %), as well as a statistically significantly higher prevalence of intracranial ICA stenoses (left ICA 24, 0 % and right ICA 17, 3 %) than did non-diabetic patients (left and right ICA 3, 3 % each). Our results confirm that there is a morphological basis in ICA for increased incidence of ICA lesions in patients with diabetes as compared to those without it. Data on the incidence of stenotic ICA lesions in diabetes suggest the importance of assessing overall ICA status using digital subtraction angiography. Such an assessment is a precognition for an optimal therapeutic approach, especially in diabetic patients who are at an increased risk of cerebrovascular disease.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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