Naslov
Lower limb salvage surgery: modular endoprosthesis in bone tumour treatment

Autori
Orlić, Dubravko ; Smerdelj, Miroslav ; Kolundžić, Robert ; Bergovec, Marko

Izvornik
International Orthopaedics (0341-2695) 30 (2006), 6; 458-464

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
bone tumour ; surgery ; malignant-tumor ; distal femur ; reconstruction ; replacement ; osteosarcoma ; chemotherapy ; extremities ; prosthesis ; experience ; survival

Sažetak
We retrospectively analysed 90 patients who underwent “ en bloc” resection and modular endoprosthesis reconstruction in the lower limbs between 1987– 2003. After proximal femur resection, reconstruction was performed with a modular endoprosthesis by Howmedica (KFTR, designed by Kotz) and modular revision endoprosthesis by W. Link or Lima-Lto (Revision system, designed by Wagner). The knee joint was reconstructed with a modular endoprosthesis (Howmedica, KFTR designed by Kotz) after distal femur or proximal tibia resection. Malignant bone tumours were present in 58 patients (64.5%), benign tumours in 16 (17.8%), metastases in 8 (8.9%), tumour-like lesions in 4 (4.4 %) and non-tumour-related destruction of the femur in 4 patients (4.4%). High-grade tumours were found in the majority of malignant bone tumours (70.7%). Treatment complications, which occurred in 26 patients, were: local recurrence of the tumour, deep infection, acetabular destruction following hemiarthroplasty, recurrent dislocations of endoprosthesis, periprosthetic fracture and hardware problems. In total, 23 patients (25.6%) died due to tumours. Endoprostheses should be considered as a treatment of choice for bone tumours in the hip and knee joint region. Advances in limb salvage surgery are, and will long continue to be, a great challenge for orthopaedic oncologists of the 21st century.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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