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Pregled bibliografske jedinice broj: 343981

Progesterone during pregnancy: endocrine-immune cross talk in mammalian species and the role of stress


Arck, Petra; Hansen, Peter; Mulac-Jeričević, Biserka; Piccinni, Marie-Pierre; Szekeres-Bartho, Julia
Progesterone during pregnancy: endocrine-immune cross talk in mammalian species and the role of stress // American Journal of Reproductive Immunology, 58 (2007), 3; 268-279 doi:10.1111/j.1600-0897.2007.00512.x (međunarodna recenzija, pregledni rad, znanstveni)


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Naslov
Progesterone during pregnancy: endocrine-immune cross talk in mammalian species and the role of stress

Autori
Arck, Petra ; Hansen, Peter ; Mulac-Jeričević, Biserka ; Piccinni, Marie-Pierre ; Szekeres-Bartho, Julia

Izvornik
American Journal of Reproductive Immunology (1046-7408) 58 (2007), 3; 268-279

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
NK cells; pregnancy; progesterone

Sažetak
Progesterone is critical for the establishment and the maintenance of pregnancy, both by its endocrine and immunological effects. The genomic actions of progesterone are mediated by the intracellular progesterone receptors ; A and B. A protein called P-induced blocking factor (PIBF), by inducing a TH2 dominant cytokine production, mediates the immunological effects of progesterone. Progesterone plays a role in uterine homing of NK cells and up-regulates HLA-G gene expression, the ligand for various NK inhibitory receptors. At high concentrations progesterone is a potent inducer of Th2-type cytokines as well as of LIF and M-CSF production by T cells. Though a key role for progesterone in creating local immunosuppression has been conserved during the evolution of an epitheliochorial placenta, there has been some divergence in the pattern of endocrine-immunological cross talk in Bovidae. In sheep, uterine serpin, a progesterone-induced endometrial protein, mediates the immunosuppressive effects of progesterone. Epidemiological studies suggest the role of stress in premature pregnancy termination and exposure to stress induces abortion in mice via a significant reduction in progesterone levels, accompanied by reduced serum levels of PIBF. These effects are corrected by progesterone supplementation. These findings indicate the significance of a progesterone-dependent immuno-modulation in maternal tolerance of the fetus, which is discussed in this review.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
062-0620402-0381 - Reprodukcijske i imunološke funkcije progesterona (Mulac-Jeričević, Biserka, MZOS ) ( CroRIS)

Ustanove:
Medicinski fakultet, Rijeka

Profili:

Avatar Url Biserka Mulac-Jeričević (autor)

Poveznice na cjeloviti tekst rada:

doi www3.interscience.wiley.com

Citiraj ovu publikaciju:

Arck, Petra; Hansen, Peter; Mulac-Jeričević, Biserka; Piccinni, Marie-Pierre; Szekeres-Bartho, Julia
Progesterone during pregnancy: endocrine-immune cross talk in mammalian species and the role of stress // American Journal of Reproductive Immunology, 58 (2007), 3; 268-279 doi:10.1111/j.1600-0897.2007.00512.x (međunarodna recenzija, pregledni rad, znanstveni)
Arck, P., Hansen, P., Mulac-Jeričević, B., Piccinni, M. & Szekeres-Bartho, J. (2007) Progesterone during pregnancy: endocrine-immune cross talk in mammalian species and the role of stress. American Journal of Reproductive Immunology, 58 (3), 268-279 doi:10.1111/j.1600-0897.2007.00512.x.
@article{article, author = {Arck, Petra and Hansen, Peter and Mulac-Jeri\v{c}evi\'{c}, Biserka and Piccinni, Marie-Pierre and Szekeres-Bartho, Julia}, year = {2007}, pages = {268-279}, DOI = {10.1111/j.1600-0897.2007.00512.x}, keywords = {NK cells, pregnancy, progesterone}, journal = {American Journal of Reproductive Immunology}, doi = {10.1111/j.1600-0897.2007.00512.x}, volume = {58}, number = {3}, issn = {1046-7408}, title = {Progesterone during pregnancy: endocrine-immune cross talk in mammalian species and the role of stress}, keyword = {NK cells, pregnancy, progesterone} }
@article{article, author = {Arck, Petra and Hansen, Peter and Mulac-Jeri\v{c}evi\'{c}, Biserka and Piccinni, Marie-Pierre and Szekeres-Bartho, Julia}, year = {2007}, pages = {268-279}, DOI = {10.1111/j.1600-0897.2007.00512.x}, keywords = {NK cells, pregnancy, progesterone}, journal = {American Journal of Reproductive Immunology}, doi = {10.1111/j.1600-0897.2007.00512.x}, volume = {58}, number = {3}, issn = {1046-7408}, title = {Progesterone during pregnancy: endocrine-immune cross talk in mammalian species and the role of stress}, keyword = {NK cells, pregnancy, progesterone} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka::


  • Biological Abstracts/BIOSIS, Elsevier BIOBASE/Current Awareness in Biological Sciences, Science Citation Index, SCISEARCH, Research Alert


Citati:





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