Pregled bibliografske jedinice broj: 341995
Possible prognostic significance of p53 and Ki 67 in inverted sinonasal papilloma
Possible prognostic significance of p53 and Ki 67 in inverted sinonasal papilloma // Collegium antropologicum, 31 (2007), 2; 545-549 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 341995 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Possible prognostic significance of p53 and Ki 67 in inverted sinonasal papilloma
Autori
Bura, Miljenko ; Seiwerth, Sven ; Vladika, Ivan ; Perović, Darko ; Nagy, Paul ; Ćorić, Marijana ; Bijelić, Lana ; Krajina, Zdenko ; Žižić Mitrečić, Marica
Izvornik
Collegium antropologicum (0350-6134) 31
(2007), 2;
545-549
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
inverted papilloma; sinus
Sažetak
The aim of this study is to test the possible prognostic significance of p53 and Ki67 expression in inverted papilloma of the lateral nasal wall and adjacent sinuses regarding their malignant potential and recurrence. 49 biopsies of the lateral nasal wall and adjacent sinuses obtained from 41 patients from three hospitals were investigated. Immunohistochemically demonstrated p53 and Ki67 expression was measured and statistically evaluated. p53 immunoreactivity was demonstrated in most of papillomas with carcinomas but only in two benign papillomas, while Ki67 demonstrated stronger immunoreactivity in carcinomas and surrounding epithelium. Immunohistochemical staining of inverted sinonasal papillomas for p53 and Ki67 can give useful information concerning the existence of synchronous carcinoma and, in case of high Ki67, a hint toward possible recurrence.
Izvorni jezik
Engleski
POVEZANOST RADA
Projekti:
108-0000000-0051 - Molekularna osnova raka štitnjače-kriteriji u terapiji diferenciranih karcinoma (Bura, Miljenko, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Zagreb
Profili:
Darko Perović
(autor)
Ivan Vladika
(autor)
Sven Seiwerth
(autor)
Zdenko Krajina
(autor)
Marijana Ćorić
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Social Science Citation Index (SSCI)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE