Pregled bibliografske jedinice broj: 340670
Moderate activities of regulatory T (Treg) and NKT cells on innate immunity in chronic exposure to vapors
Moderate activities of regulatory T (Treg) and NKT cells on innate immunity in chronic exposure to vapors // 13th International Congress of Immunology, Rio de Janeiro (Brazil), August 21-25, 2007 / Jorge Kalil, Edecio Cunha-Neto, Luiz Vicente Rizzo (ur.).
Bolonja: Medimond International Proceedings, 2007. str. 317-321
CROSBI ID: 340670 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Moderate activities of regulatory T (Treg) and NKT cells on innate immunity in chronic exposure to vapors
Autori
Mićović, Vladimir ; Bulog, Aleksandar ; Mrakovčić-Šutić, Ines
Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni
Knjiga
13th International Congress of Immunology, Rio de Janeiro (Brazil), August 21-25, 2007
Urednik/ci
Jorge Kalil, Edecio Cunha-Neto, Luiz Vicente Rizzo
Izdavač
Medimond International Proceedings
Grad
Bolonja
Godina
2007
Raspon stranica
317-321
ISBN
978-88-7587-379-0
Ključne riječi
Tregs, NKT cells, innate immunity, environmental diseases
Sažetak
The ability of extracellular stimuli to modulate innate immunity via activation of regulatory T (Tregs) and natural killer T (NKT) cells was not well understood. The immune system's capacity to distinguish between innocuous and harmful foreign antigens is controlled by mechanisms of central and peripheral tolerance. Mechanisms of peripheral tolerance involve the induction of cell death or the development of a no responsive state (anergy) of T cells. Tregs have active suppression mode and may induce peripheral tolerance. In this study, we attempted to analyze the characteristics of human Tregs and NKT cells, by phenotypic analysis of peripheral blood cells of inhabitants leaving near gasoline industry. Our data have shown that the chronic inhalation exposure increases the percentage of Tregs and NKT cells, which may contribute to the new therapeutic approach of environmental diseases.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita
POVEZANOST RADA
Projekti:
062-0620096-0094 - Regulacijske T i NKT stanice u kontroli tumorskog rasta, opeklina i autoimunosti (Mrakovčić-Šutić, Ines, MZOS ) ( CroRIS)
062-0621341-0308 - Odgovor ljudi i morskih organizama na ekološko zagađenje u Kvarnerskom zaljevu (Mićović, Vladimir, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Rijeka
