Naslov
Biocard 41: E-cadherin

Autori
Pećina-Šlaus, Nives

Izvornik
Melanoma Molecular Map Project - An open access interactive multidatabase for research on melanoma biology and treatment

Vrsta, podvrsta
Ostale vrste radova, katalog

Godina
2007

Ključne riječi
melanoma; E-cadherin

Sažetak
This gene can play a major role in malignant cell transformation, and especially in tumor development and progression. Most tumors (including melanoma) have abnormal cellular architecture, and loss of tissue integrity can lead to local invasion. Thus, loss of function of E-cadherin tumor suppressor protein correlates with increased invasiveness and metastasis of tumors, resulting in it being referred to as the "suppressor of invasion" gene.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA