Naslov
Transbronchial fine needle aspiration cytology in the diagnosis of mediastinal/hilar sarcoidosis

Autori
Smojver-Ježek, Silvana ; Peroš-Golubičić, Tatjana ; Tekavec-Trkanjec, Jasna ; Mažuranić, Ivica ; Alilović, Marija

Izvornik
Cytopathology (0956-5507) 18 (2007), 1; 3-7

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
sarcoidosis; transbronchial fine needle aspiration cytology
(arcoidosis; transbronchial fine needle aspiration cytology)

Sažetak
Objective: The diagnostic value of transbronchial/transtracheal fine needle aspiration (TBFNA) cytology in the patients with mediastinal and/or hilar lymphadenopathy has been investigated. Method: Out of 116 patients with mediastinal/hilar lymphadenopathy, the diagnosis of sarcoidosis was established in 88 (75.9%). One hundred and seventy-one TBFNAs from different lymph node stations were performed using a cytological 26-gauge needle. Adequate lymph node samples were obtained in 157 of 171 (91.8%) TBFNA and 14 of 171 (8.2%) TBFNA samples were inadequate. Results: Cytological findings consistent with sarcoidosis were found in 79 of 88 (89.77%) patients and 133 of 157 (84.71%) samples. The sensitivity of TBFNA cytology in sarcoidosis presenting as mediastinal/hilar lymphadenopathy was 78.7%, specificity 92.3%. Conclusions: Overall diagnostic accuracy of TBFNA cytology in the diagnosis of sarcoidosis was 86.2%, and cytological findings consistent with sarcoidosis were the only morphological diagnosis of sarcoidosis in 63.6% of patients.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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