Pregled bibliografske jedinice broj: 315163
Succesfull use of activated recombinant factor VII in life-threatening bleeding after thoracic surgery
Succesfull use of activated recombinant factor VII in life-threatening bleeding after thoracic surgery // Swiss medical weekly, 137 (2007), 27-28; 407-410 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 315163 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Succesfull use of activated recombinant factor VII in life-threatening bleeding after thoracic surgery
Autori
Majerić Kogler, Višnja ; Slobodnjak, Zoran ; Samaržija, Miroslav ; Špiček Macan, Jasna ; Karadža, Vjekoslav ; Jakopović, Marko
Izvornik
Swiss medical weekly (1424-7860) 137
(2007), 27-28;
407-410
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
recombinant factor VII; thoracic surgery
Sažetak
We present three patients in whom life-threatening haemorrhage following lung resection was successfully managed using activated recombinant factor VII (NovoSeven((R))). In one case, activated recombinant factor VII was the only therapy administered to manage bleeding, ani in the two remaining cases, activated recombinant factor VII was administered after patients failed to respond to conventional therapy. All patients demonstrated effective haemostasis and improved coagulation parameters as a result of treatment with activated recombinant factor VII. Our experience with the clinical use of rFVIIa suggests that this agent may provide effective hemostasis following lifethreatening postoperative bleeding after major thoracic surgery. Despite these favorable results, randomized, placebo controlled trials are needed to identify optimal treatment strategy, patient selection, and safety of treatment in patients with massive bleeding following major thoracic surgery.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
108-0000000-0008 - Utjecaj liječenja akutne boli na tijek i ishod liječenja kirurških bolesnika (Majerić-Kogler, Višnja, MZOS ) ( CroRIS)
098-0982464-2394 - Gensko liječenje tumora djelovanjem na molekule imunološkog sustava (Pavelić, Jasminka, MZOS ) ( CroRIS)
Ustanove:
Klinika za plućne bolesti "Jordanovac"
Profili:
Višnja Majerić-Kogler
(autor)
Marko Jakopović
(autor)
Miroslav Samaržija
(autor)
Zoran Slobodnjak
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE