A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia

Antica, Mariastefania; Dubravčić, Klara; Weber, Igor; Rajić, Ljubica; Labar, Boris; Batinić, Drago

Pregled bibliografske jedinice broj: 314276

A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia

Antica, Mariastefania; Dubravčić, Klara; Weber, Igor; Rajić, Ljubica; Labar, Boris; Batinić, Drago

A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia // Haematologica, 92 (2007), 2; 260-261 (međunarodna recenzija, pismo, znanstveni)

CROSBI ID: 314276 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia

Autori
Antica, Mariastefania ; Dubravčić, Klara ; Weber, Igor ; Rajić, Ljubica ; Labar, Boris ; Batinić, Drago

Izvornik
Haematologica (0390-6078) 92 (2007), 2; 260-261

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pismo, znanstveni

Ključne riječi
leukemia; Aiolos; transcription factors

Sažetak
We examined whether phosphorylation of Aiolos in primary human lymphocytes is part of the malignant transformation in leukemia. By analyzing mutations at a restriction site we show here that impairment of Aiolos activity in human leukemia is not based on deficient phosphorylation as had been demonstrated in experiments in vitro.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti

POVEZANOST RADA

Projekti:
098-0982913-2332 - Molekularne interakcije u diferencijaciji limfocita (Antica, Mariastefania, MZOS ) ( CroRIS)
098-0982913-2858 - Regulacija dinamike citoskeleta u kretanju i diobi stanica (Weber, Igor, MZOS ) ( CroRIS)
108-1081872-1913 - LEUKEMIJE I TRANSPLANTACIJA KRVOTVORNIH MATIČNIH STANICA (Duraković, Nadira, MZOS ) ( CroRIS)
214-1081347-0355 - Uloga PI3K/Akt i MAPK u regulaciji kemorezistencije leukemijskih stanica (Batinić, Drago, MZOS ) ( CroRIS)