Naslov
Imines derived from enantiopure trans-3-amino-azetidin-2-ones as dienophiles in aza-Diels-Alder reactions with activated and nonactivated dienes

Autori
Poljak, Tanja ; Molčanov, Krešimir ; Margetić, Davor ; Habuš, Ivan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
ESOC 15 ; Abstracts / Guiry, Pat ; Mooney, Ann - Dublin : University College Dublin, 2007

Skup
The 15th European Symposium on Organic Chemistry

Mjesto i datum
Dublin, Irska, 08.07.2007. - 13.07.2007

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
beta-laktam; imin; Diels-Alderova reakcija; Lewisova kiselina
(beta-Lactam; Imine; Diels-Alder reaction; Lewis acid)

Sažetak
Beta-lactams are increasingly being used as synthons for the synthesis of variety of natural products. Efforts have been made in exploring such new aspects of beta-lactam chemistry using enantiomerically pure beta-lactams as versatile intermediates for the synthesis of aromatic beta-amino acids and their derivatives, oligopeptides, labelled peptides and azetidines, which are further converted to polyamines, polyamino alcohols, amino sugars and polyamino ethers. On the other hand, six-membered nitrogen heterocycles, pyridines and pyridones, represent the key building units in medicinal chemistry and interesting intermediates in organic synthesis. They are found in natural alkaloids, which possess strong pharmacological activity, peptides and aza-sugars.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA