Pregled bibliografske jedinice broj: 304203
The Use of Convective Interaction Media for Analysis of Long-Nosed Viper Venom
The Use of Convective Interaction Media for Analysis of Long-Nosed Viper Venom // Journal of Liquid Chromatography and Related Technologies, 31 (2008), 1; 38-53 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 304203 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The Use of Convective Interaction Media for Analysis of Long-Nosed Viper Venom
Autori
Halassy, Beata ; Brgles, Marija ; Habjanec, Lidija ; Lang Balija, Maja ; Tomašić, Jelka ; Križaj, Igor ; Štrancar, Aleš ; Barut, Miloš
Izvornik
Journal of Liquid Chromatography and Related Technologies (1082-6076) 31
(2008), 1;
38-53
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Vipera ammodytes ammodytes; ammodytoxins; Convective Interaction Media; antivenom production; long-nosed viper
Sažetak
Confirmed also in this study, Vipera ammodytes ammodytes venom samples with higher content of ammodytoxins (Atxs), basic neurotoxic phospholipases A2, are more lethal, exposing Atxs as one of the major toxic components in the long-nosed viper venom. In addition, we recently correlated the ability of the venom to produce highly protective antiserum in rabbits with the amount of Atxs in the venom. Here, we developed a rapid, robust and highly reproducible chromatographic method based on HPLC separation on Convective Interaction Media to assess the quantity of Atxs in particular venom sample in order to predict its potential to induce highly-protective antiserum in immunized animals.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti, Drvna tehnologija
Napomena
Special Issue: Analysis of Polar Compounds
POVEZANOST RADA
Projekti:
021-0212432-2033 - Imunogeničnost komponenti kompleksnih antigena (Halassy, Beata, MZOS ) ( CroRIS)
021-0212432-2431 - Nove formulacije antigena i imunostimulatora - utjecaj na imunoreakciju (Frkanec, Ruža, MZOS ) ( CroRIS)
Ustanove:
Imunološki zavod d.d.
Profili:
Jelka Tomašić
(autor)
Lidija Habjanec
(autor)
Marija Brgles
(autor)
Beata Halassy
(autor)
Maja Lang Balija
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus