Pregled bibliografske jedinice broj: 30260
A serum-free mammalian embryo culture : a possible model for embryo-(neuro- toxicity testing)
A serum-free mammalian embryo culture : a possible model for embryo-(neuro- toxicity testing) // ATLA / Balls, Michael (ur.).
Nottingham: FRAME, 1996. str. 241-241 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 30260 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
A serum-free mammalian embryo culture : a possible model for embryo-(neuro- toxicity testing)
Autori
Bulić-Jakuš, Floriana ; Vlahović, Maja ; Jurić-Lekić, Gordana ; Strahinić, Tatjana
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
ATLA
/ Balls, Michael - Nottingham : FRAME, 1996, 241-241
Skup
Second World Congress on Alternatives and Animal Use in the Life Sciences
Mjesto i datum
Utrecht, Nizozemska, 20.10.1996. - 24.10.1996
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
serum-free;in vitro; mammalian embryo; embryo-toxicity testing; rat
Sažetak
We have developed a postimplantation rat embryo culture model in a simple serum-free chemically defined medium which we have used primarily to investigate the influence of biologicaly active substances upon growth and differentiation. As our in vitro results showed essentially the same effect on the differentiation of neural tissue as our in vivo results (grafts of cultivated embryos) we deduced that our in vitro three-dymensional model system in chemically defined medium can probably be used as an alternative to in vivo experiments for embryotoxicity and especially neurotoxicity-testing during the most critical period of mammalian embryonic development.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
