Naslov
Guanidines - from Theory to Synthesis and Applications

Autori
Eckert-Maksić, Mirjana ; Glasovac, Zoran ; Strukil, Vjekoslav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
50th Anniversary meeting Challenges in Organic Chemistry & Eight Tetrahedron Symposium : Abstracts / Waldmann, Herbert - Berlin : Elsevier, 2007, P3.139-P3.139

Skup
50th Anniversary meeting Challenges in Organic Chemistry & Eight Tetrahedron Symposium

Mjesto i datum
Berlin, Njemačka, 26.06.2007. - 29.06.2007

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
guanidine bases; proton affinities; pKa values; catalitic activity

Sažetak
Preparation and characterization of strong neutral organic bases has been a subject matter of considerable interest in recent years. This is not surprising, since strong neutral bases have some important advantages over their ionic counterparts. They require milder reaction conditions and enable reactions to be carried out in homogeneous environment. Special attention in these studies has been devoted to acyclic and cyclic guanidines, biguanidines, vinamidines and phosphazenes. In this talk an overview of our recent studies in guanidine chemistry aiming at developing potent basic catalysts, will be presented. The following issues will be addressed:(a) synthesis and structure elucidation of guanidine bases capable of forming multiple intramolecular hydrogen bonds ; (b) exploration of catalytic activity of some of these bases in selected reactions, like transesterification, Knoevenagel and nitroaldol reaction and (c) synthesis and structure elucidation of new triguanide derivatives. Experimental data will be complemented by calculation of the gas phase proton affinities and pKa values in acetonitrile.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA