Pregled bibliografske jedinice broj: 299586
Quinine-Mediated Parallel Kinetic Resolution of Racemic Cyclic Anhydride: Stereoselective Synthesis, Relative and Absolute Configuration of Novel Alicyclic b-amino acids
Quinine-Mediated Parallel Kinetic Resolution of Racemic Cyclic Anhydride: Stereoselective Synthesis, Relative and Absolute Configuration of Novel Alicyclic b-amino acids // Tetrahedron: asymmetry, 18 (2007), 635-644 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 299586 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Quinine-Mediated Parallel Kinetic Resolution of Racemic Cyclic Anhydride: Stereoselective Synthesis, Relative and Absolute Configuration of Novel Alicyclic b-amino acids
Autori
Hameršak, Zdenko ; Roje, Marin ; Avdagić, Amir ; Šunjić, Vitomir
Izvornik
Tetrahedron: asymmetry (0957-4166) 18
(2007);
635-644
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
rac. cyclic anhydride; kinetic resolution; quinine; cyclic b-amino acids; absolute configuration.
Sažetak
Four endo-isomers of (1R, 2S)-2-amino-4-methylenecyclopentanecarboxylic acid (Icofungipen (+)-1) have been prepared in the enantiomerically pure form. Three endo-isomers are obtained by quinine-mediated kinetic resolution of racemic anhydride, followed by Curtius rearrangement. The fourth one was obtained by exo-endo isomerization of (+)-1. Assignment of absolute configuration is based either on the Cotton effect in the CD spectra, or on correlation to known structures.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
098-0982933-2908 - Kiralni građevni blokovi za biološki aktivne molekule. Sinteza i reaktivnost (Hameršak, Zdenko, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
